ArticleDementia and geriatric cognitive disorders2021
Using Fractional Anisotropy Imaging to Detect Mild Cognitive Impairment and Alzheimer's Disease among Mexican Americans and Non-Hispanic Whites: A HABLE Study.
Article in Dementia and geriatric cognitive disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Metabolic dysfunction associates with neuroimaging measures of brain structure and connectivity.Frontiers in neuroscience · 2026Article
- Fractional Anisotropy Alterations in Key White Matter Pathways Associated with Cognitive Performance Assessed by MoCA.Neurology international · 2025Article
- Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Understanding Cognitive Aging Through White Matter: A Fixel-Based Analysis.Human brain mapping · 2024Article
- Sex, racial, andbioRxiv : the preprint server for biology · 2024Article
- Evaluation of Neighborhood-Level Disadvantage and Cognition in Mexican American and Non-Hispanic White Adults 50 Years and Older in the US.JAMA network open · 2023Article
- Acculturation in Context and Brain Health in Older Latino Adults: A Diffusion Tensor Imaging Study.Journal of Alzheimer's disease : JAD · 2023Article
- Hyperparameter Tuning with High Performance Computing Machine Learning for Imbalanced Alzheimer's Disease Data.Applied sciences (Basel, Switzerland) · 2022Article
- Metabolic Factors Are Related to Brain Amyloid Among Mexican Americans: A HABS-HD Study.Journal of Alzheimer's disease : JAD · 2022Article
- The Link between APOE4 Presence and Neuropsychological Test Performance among Mexican Americans and Non-Hispanic Whites of the Multiethnic Health & Aging Brain Study - Health Disparities Cohort.Dementia and geriatric cognitive disorders · 2022Article
- APOEε4 Genotype Is Related to Brain Amyloid Among Mexican Americans in the HABS-HD Study.Frontiers in neurology · 2022Article
- Characterization of Mild Cognitive Impairment and Dementia among Community-Dwelling Mexican Americans and Non-Hispanic Whites.Journal of Alzheimer's disease : JAD · 2022Article
- Top Alzheimer's disease risk allele frequencies differ in HABS-HD Mexican- versus Non-Hispanic White Americans.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
introductionAlzheimer's disease (AD) is the most frequently occurring neurodegenerative disease; however, little work has been conducted examining biomarkers of AD among Mexican Americans. Here, we examined diffusion tensor MRI marker profiles for detecting mild cognitive impairment (MCI) and dementia in a multi-ethnic cohort.
methods3T MRI measures of fractional anisotropy (FA) were examined among 1,636 participants of the ongoing community-based Health & Aging Brain among Latino Elders (HABLE) community-based study (Mexican American n = 851; non-Hispanic white n = 785).
resultsThe FA profile was highly accurate in detecting both MCI (area under the receiver operating characteristic curve [AUC] = 0.99) and dementia (AUC = 0.98). However, the FA profile varied significantly not only between diagnostic groups but also between Mexican Americans and non-Hispanic whites.
conclusionFindings suggest that diffusion tensor imaging markers may have a role in the neurodiagnostic process for detecting MCI and dementia among diverse populations.
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