Evidence map›Paper›PMID 34569443›Full record

ArticleGlobal health action2021

Forty years after Alma-Ata: primary health-care preparedness for chronic diseases in Mozambique, Nepal and Peru.

Maria Kathia Cárdenas, Silvana Pérez-León, Suman Bahadur Singh, Tavares Madede, Savaiva Munguambe, Valério Govo, Nilambar Jha, Albertino Damasceno, J Jaime Miranda, David Beran

Registry-linked trialAbstract read
In one paragraph

Article in Global health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06989502 (GH Project), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06989502 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

GH Project: NIHR150261 - Implementation of the COmmunity HEalth System InnovatiON Project, COHESION-I

TypeinterventionalSponsorUniversidad Peruana Cayetano HerediaRan2025 to 2026Enrolled2,094ConditionsHypertension, Diabetes Mellitus, Neglected Tropical DiseasesArmsCo-creation (2016 to 2019) + Co-design (2023 to 2024), Co-design only (2023 to 2024)
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Observational
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Kathia CárdenasCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0002-3173-9284
Silvana Pérez-LeónCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0003-4860-587X
Suman Bahadur SinghB. P. Koirala Institute of Health Sciences, Dharan, Nepal.ORCID 0000-0002-5375-1110
Tavares MadedeFaculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.ORCID 0000-0001-8194-8597
Savaiva MunguambeFaculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.ORCID 0000-0002-2565-9878
Valério GovoResearch Unit, Department of Internal Medicine, Maputo Central Hospital, Maputo, Mozambique.ORCID 0000-0002-0238-5528
Nilambar JhaB. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Albertino DamascenoFaculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.ORCID 0000-0003-0925-494X
J Jaime MirandaCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0002-4738-5468
David BeranDivision of Tropical and Humanitarian Medicine, Faculty of Medicine, University of Geneva, Geneva University Hospitals, Geneva, Switzerland.ORCID 0000-0001-7229-3920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFour decades after the Alma-Ata Declaration, strengthening primary health care (PHC) remains a priority for health systems, especially in low- and middle-income countries (LMICs). Given the prominence of chronic diseases as a global health issue, PHC must include a wide range of components in order to provide adequate care.

objectiveTo assess PHC preparedness to provide chronic care in Mozambique, Nepal and Peru, we used, as 'tracer conditions', diabetes, hypertension and a country-specific neglected tropical disease with chronic sequelae in each country.

methodsBy implementing a health system assessment, we collected quantitative and qualitative data from primary and secondary sources, including interviews of key informants at three health-system levels (macro, meso and micro). The World Health Organization's health-system building blocks provided the basis for content analysis.

resultsIn total, we conducted 227 interviews. Our findings show that the ambitious policies targeting specific diseases lack the support of technical, administrative and financial resources. Data collection systems do not allow the monitoring of individual patients or provide the health system with the information it requires. Patients receive limited disease-specific information. Clinical guidelines and training are either non-existent or not adapted to local contexts. Availability of medicines and diagnostic tests at the PHC level is an issue. Although medicines available through the public health care system are affordable, some essential medicines suffer shortages or are not available to PHC providers. This need, along with a lack of clear referral procedures and available transportation, generates financial issues for individuals and affects access to health care.

conclusionPHC in these LMICs is not well prepared to provide adequate care for chronic diseases. Improving PHC to attain universal health coverage requires strengthening the identified weaknesses across health-system building blocks.

Indexed as

Primary Health CareChronic DiseaseHumansMozambiqueNepalPeruchronic conditionsdeveloping countriesHealth systemsprimary health-care

Identifiers

PMID34569443
PMCPMC8477950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.