Evidence map›Paper›PMID 34569428›Full record

ArticlePharmaceutical biology2021

SIRT 3 was involved in

Zhang-Jie Yang, Yu-Xin Wang, Shuai Zhao, Na Hu, Dong-Mei Chen, Hui-Ming Ma

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhang-Jie YangKey Laboratory of Fertility Preservation and Maintenance of Ministry of Education in Ningxia Medical University, Yinchuan, China.
Yu-Xin WangKey Laboratory of Fertility Preservation and Maintenance of Ministry of Education in Ningxia Medical University, Yinchuan, China.
Shuai ZhaoKey Laboratory of Fertility Preservation and Maintenance of Ministry of Education in Ningxia Medical University, Yinchuan, China.
Na HuKey Laboratory of Fertility Preservation and Maintenance of Ministry of Education in Ningxia Medical University, Yinchuan, China.
Dong-Mei ChenInstitute of Human Stem Cell Research, The General Hospital of Ningxia Medical University, Yinchuan, China.
Hui-Ming MaKey Laboratory of Fertility Preservation and Maintenance of Ministry of Education in Ningxia Medical University, Yinchuan, China.
Ningxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveThis study evaluates the effects and mechanism of LBSO in the d-galactose (d-gal)-induced ageing testis. MATERIALS AND

methodsMale Sprague Dawley (SD) rats (

resultsTreatment with LBSO, the levels of INHB and testosterone both increased, compared to ageing model. DISCUSSION AND

conclusionsLBSO alleviated oxidative stress in d-gal-induced sub-acutely ageing testis and TM4 cells by suppressing the oxidative stress to mitochondria via SIRT3/AMPK/PGC-1α.

Indexed as

AgingAMP-Activated Protein Kinase KinasesAnimalsCell LineLyciumMaleMiceMitochondriaOxidative StressPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPlant OilsRatsRats, Sprague-DawleySeedsSertoli CellsSirtuinsAMP-Activated Protein Kinase KinasesPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPlant OilsPpargc1a protein, ratSIRT3 protein, ratSirtuinsanti-ageingethic medicineSertoli cells (TM4)

Identifiers

PMID34569428
PMCPMC8475125
OpenAlexW3203805361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.