Evidence map›Paper›PMID 34568960›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2022

How do presentation age and CSF opening pressure level affect long-term prognosis of pseudotumor cerebri syndrome in children? Experience of a single tertiary clinic.

Gulten Ozturk, Dilşad Turkdogan, Olcay Unver, Volkan Dericioglu, Bulent Aslan, Adnan Dagcinar

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Gulten OzturkDepartment of Pediatric Neurology, Marmara University Medical Faculty Pendik Education and Research Hospital, Istanbul, Turkey. gulten@thomas.md.ORCID http://orcid.org/0000-0002-3800-693X
Dilşad TurkdoganDepartment of Pediatric Neurology, Marmara University Medical Faculty Pendik Education and Research Hospital, Istanbul, Turkey.
Olcay UnverDepartment of Pediatric Neurology, Marmara University Medical Faculty Pendik Education and Research Hospital, Istanbul, Turkey.
Volkan DericiogluDepartment of Ophtalmology, Marmara University Pendik Education and Research Hospital, Istanbul, Turkey.
Bulent AslanDepartment of Radiology, Marmara University Pendik Education and Research Hospital, Istanbul, Turkey.
Adnan DagcinarDepartment of Neurosurgery, Marmara University Medical Faculty Pendik Education and Research Hospital, Istanbul, Turkey.

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6 · The paper itself

Abstract

backgroundDiagnosis and treatment of pseudotumor cerebri syndrome in children is still a challenge for clinicians. The aim of this study is to reveal the influence of presentation age and CSF opening pressure on long-term prognosis of pseudotumor cerebri and share our clinical data of the very young age (≤ 5-year) group.

methodThis retrospective study includes the patients followed by the Marmara University Pediatric Neurology Clinic between years 2012 and 2020 diagnosed with definite, probable, or suggestive pseudotumor cerebri syndrome according to modified Friedman criteria. Patients were classified into three groups according to presentation age: group 1: ≤ 5 years old; group 2: 6-10 years; and group 3 > 10 years old. CSF opening pressure was also categorized into three groups as CSF < 20 cmH20; CSF 20-30 cmH20; and CSF > 30 cmH20.

resultsOne hundred three patients, 62.1% female (n = 64), were enrolled in the study. Group 1 consisted of 16 patients (60% male), group 2 consisted of 30 patients (63.3% female), and group 3 consisted of 57 patients (66.7% female). The mean CSF opening pressure did not differ between the three age groups in our study (p > 0.05). Treatment response was not correlated with CSF opening pressure. Papilledema presence and level of CSF opening pressure were independent of age (p > 0.05).

conclusionsAge at presentation and CSF opening pressure at diagnosis are not any predictive factors that influence long-term prognosis of pseudotumor cerebri syndrome in children. Evaluation and follow-up of children should be done in personalized approach.

Indexed as

PapilledemaPseudotumor CerebriCerebrospinal Fluid PressureChildChild, PreschoolFemaleHumansMalePrognosisRetrospective StudiesAgeAnd correlation of our findings is done compared to the literatureChildrenCSF pressurePapilledemaPseudotumor cerebri

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