Evidence map›Paper›PMID 34568782›Full record

ArticleiScience2021

Molecular competition can shape enhancer activity in the

Rachel Waymack, Mario Gad, Zeba Wunderlich

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Brain-Specific Gata4 Downregulation in Greywick Female Mice Models the Metabolic Subtype of Polycystic Ovary Syndrome.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Article
  3. The Hill function is the universal Hopfield barrier for sharpness of input-output responses.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rachel WaymackDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA.
Mario GadDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA.
Zeba WunderlichDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA.
University of California, Irvine · USBoston University · US

Funding

Mechanisms of shadow enhancer robustness during developmentR01HD095246 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI Zeba B Wunderlich · 2018 to 2026
$2.7M
NICHD NIH HHS R01 HD095246
6 · The paper itself

Abstract

Transgenic reporters allow the measurement of regulatory DNA activity

Indexed as

Biological sciencesCell biologyDevelopmental biologyMathematical biosciencesMolecular biologyMolecular interaction

Identifiers

PMID34568782
PMCPMC8449247
OpenAlexW3193643010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.