Evidence map›Paper›PMID 34568773›Full record

ArticleACS applied bio materials2021

Shape Memory Polymer Foams with Tunable Degradation Profiles.

Anand Utpal Vakil, Natalie Marie Petryk, Ellen Shepherd, Henry T Beaman, Priya S Ganesh, Katheryn S Dong, Mary Beth B Monroe

Abstract read
In one paragraph

Article in ACS applied bio materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. An All-In-One Transient Theranostic Platform for Intelligent Management of Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anand Utpal VakilDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.ORCID 0000-0002-6303-8562
Natalie Marie PetrykDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.
Ellen ShepherdDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.
Henry T BeamanDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.
Priya S GaneshDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.
Katheryn S DongDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.
Mary Beth B MonroeDepartment of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York 13244, United States.ORCID 0000-0003-4540-5303

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uncontrolled hemorrhage is the leading cause of preventable death on the battlefield and results in ∼1.5 million deaths each year. The primary current treatment options are gauze and/or tourniquets, which are ineffective for up to 80% of wounds. Additionally, most hemostatic materials must be removed from the patient within <12 h, which limits their applicability in remote scenarios and can cause additional bleeding upon removal. Here, degradable shape memory polymer (SMP) foams were synthesized to overcome these limitations. SMP foams were modified with oxidatively labile ether groups and hydrolytically labile ester groups to degrade after implantation. Foam physical, thermal, and shape memory properties were assessed along with cytocompatibility and blood interactions. Degradation profiles were obtained in vitro in oxidative and hydrolytic media (3% H

Indexed as

HemostaticsSmart MaterialsBandagesHemorrhageHemostasisHumansHydrogen PeroxideHemostaticsHydrogen PeroxideSmart Materials

Identifiers

PMID34568773
PMCPMC8456454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.