Evidence map›Paper›PMID 34568730›Full record

ArticleInternational journal of reproductive biomedicine2021

Relative frequency of hepatitis B virus, human papilloma virus, Epstein-Barr virus, and herpes simplex viruses in the semen of fertile and infertile men in Shiraz, Iran: A cross-sectional study.

Hossein Afrakhteh, Negar Joharinia, Akhtar Momen, Razieh Dowran, Abouzar Babaei, Parisa Namdari, Mohammad Motamedifar, Bahia Namavar Jahromi, Jamal Sarvari

Open access · goldAbstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hossein AfrakhtehDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Negar JohariniaDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Akhtar MomenDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Razieh DowranDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Abouzar BabaeiDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Parisa NamdariDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad MotamedifarDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.
Bahia Namavar JahromiDepartment of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Jamal SarvariDepartment of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0002-2259-0836
Shiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbout 8-12% of couples on reproductive age suffers from infertility worldwide. Since 1993, the role of genital tract infections by microbes, including viruses that can infect the sperm, in human infertility has been proposed.

objectiveTo investigate the frequency of hepatitis B virus (HBV), human papilloma virus (HPV), Epstein-Barr virus (EBV), and herpes simplex virus (HSV) infection in the semen of fertile and infertile men referred to the Mother and Child Hospital, Shiraz, Iran. MATERIALS AND

methodsIn this cross-sectional study, 350 men including 200 infertile and 150 fertile men were included. All semen samples were allowed to liquefy, followed by the assessment of sperm parameters. DNA was extracted using a DNA extraction kit (CinaGene, Tehran, Iran) according to the manufacturer's instructions. Detection of HBV, HPV, EBV, and HSV1/2 was done by the PCR method.

resultsThe mean age of the participants was 36

conclusionThe results of this study indicated that HBV, HPV, EBV, and HSV might not be involved in men's infertility. Further studies are recommended for clarifying the role of these viruses in infertility.

Indexed as

Epstein-Barr virusHepatitis B virusHerpes simplex viruses.Human papilloma virusMale infertility

Identifiers

PMID34568730
PMCPMC8458917
OpenAlexW3196307681

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.