ArticleAmerican journal of health economics2021
THE EVOLVING CONSEQUENCES OF OXYCONTIN REFORMULATION ON DRUG OVERDOSES.
Article in American journal of health economics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Multinational appraisal of the epidemiological distribution of opioid fatalities: a systematic review and meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Insurance coverage and provision of opioid disorder treatment: Evidence from Medicare.Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management] · 2026Article
- Regulating quasi-legal markets: Evidence from pain management clinic laws.Journal of public economics · 2025Article
- From addiction to aggression: The spillover effects of opioid policies on intimate partner violence.Journal of health economics · 2025Article
- Hidden Costs of Ban the Box Laws: Unraveling the Effects on Drug-Related Deaths.Health economics · 2025Article
- Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans.Health affairs (Project Hope) · 2025Article
- The Growth of Illicit Drug Use and Its Effects on Murder Rates.Health economics · 2025Article
- Fighting abuse with prescription tracking: mandatory drug monitoring and intimate partner violence.Journal of population economics · 2025Article
- Understanding the demographics of the opioid overdose death crisis.Journal of population economics · 2025Article
- Investigating the complexity of naloxone distribution: Which policies matter for pharmacies and potential recipients.Journal of health economics · 2024Article
- Prenatal opioid exposure by likelihood of exposure and risk to prenatal development: Medicaid-covered births in Wisconsin, 2010-2019.Science advances · 2024Article
- Predicting first use of heroin from prescription opioid use subtypes: Insights from the Monitoring the Future longitudinal panel.Drug and alcohol dependence · 2024Article
- Article
- Early OxyContin Marketing Linked To Long-Term Spread Of Infectious Diseases Associated With Injection Drug Use.Health affairs (Project Hope) · 2023Article
- Does paid sick leave encourage staying at home? Evidence from the United States during a pandemic.Health economics · 2023Article
- Demographic and Geographic Variation in Fatal Drug Overdoses in the United States, 1999-2020.The Annals of the American Academy of Political and Social Science · 2022Article
- The effects of opioid policy changes on transitions from prescription opioids to heroin, fentanyl and injection drug use: a qualitative analysis.Substance abuse treatment, prevention, and policy · 2022Article
- ORIGINS OF THE OPIOID CRISIS AND ITS ENDURING IMPACTS.The quarterly journal of economics · 2022Article
- Preventing Overdose Using Information and Data from the Environment (PROVIDENT): protocol for a randomized, population-based, community intervention trial.Addiction (Abingdon, England) · 2022Article
- Prescription opioid policies and associations with opioid overdose and related adverse effects.The International journal on drug policy · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Recent evidence suggests that the short-term transition of the opioid crisis from prescription opioids to heroin can be attributed to the reformulation of OxyContin, which substantially reduced access to abusable prescription opioids. In this paper, we find that over a longer time horizon, reformulation stimulated illicit drug markets to grow and evolve. We compare overdose trajectories in areas more exposed to reformulation, defined as states with higher rates of nonmedical OxyContin use before reformulation, to less exposed areas. More exposed areas experienced disproportionate increases in fatal overdoses involving synthetic opioids (fentanyl) and nonopioid substances like cocaine, suggesting that these new epidemics are related to the same factors driving the rise in heroin deaths. Instead of just short-term substitution from prescription opioid to heroin overdoses, the transition to illicit markets spurred by reformulation led to growth in the overall overdose rate to unprecedented levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.