Evidence map›Paper›PMID 34568498›Full record

ArticleJournal of diabetes research2021

Oxidative and Cellular Stress Markers in Postmenopause Women with Diabetes: The Impact of Years of Menopause.

Carolain Felipin Vincensi Anklam, Yana Picinin Sandri Lissarassa, Analú Bender Dos Santos, Lílian Corrêa Costa-Beber, Lucas Machado Sulzbacher, Pauline Brendler Goettems-Fiorin, Thiago Gomes Heck, Matias Nunes Frizzo, Mirna Stela Ludwig

Abstract read
In one paragraph

Article in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Lower Plasma Antioxidant Defense and Heat Shock Proteins Mark Intra-Amniotic Sludge Ultrasound Finding.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Menopause, androgens, and cardiovascular ageing: a narrative review.Therapeutic advances in endocrinology and metabolism · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carolain Felipin Vincensi AnklamResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Yana Picinin Sandri LissarassaResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Analú Bender Dos SantosResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Lílian Corrêa Costa-BeberResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Lucas Machado SulzbacherResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Pauline Brendler Goettems-FiorinResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Thiago Gomes HeckResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.ORCID https://orcid.org/0000-0002-1242-5423
Matias Nunes FrizzoResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.
Mirna Stela LudwigResearch Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande Do Sul State (UNIJUI), Rua do Comércio, 3000 Bairro Universitário Ijuí RS, Brazil 98700-000.ORCID https://orcid.org/0000-0003-0300-1511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women live approximately one-third of their lives in postmenopause. Among postmenopausal women, type 2 diabetes mellitus (DM2) is one of the most prevalent chronic diseases. These conditions promote alterations in the oxidative, metabolic, and immune-inflammatory profiles marked by higher extracellular 72 kDa-heat shock protein (eHSP72). Here, we investigated whether the time of menopause is associated with oxidative cellular stress marker levels in postmenopausal women with DM2. Sixty-four women were recruited (56.7 ± 12.6 years old) in the pre- (

Indexed as

Oxidative StressAdultAgedBrazilDiabetes Mellitus, Type 2FemaleHSP72 Heat-Shock ProteinsHumansMiddle AgedPostmenopauseHSP72 Heat-Shock Proteins

Identifiers

PMID34568498
PMCPMC8460375

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.