Evidence map›Paper›PMID 34568434›Full record

ReviewFrontiers in robotics and AI2021

μRALP and Beyond: Micro-Technologies and Systems for Robot-Assisted Endoscopic Laser Microsurgery.

Leonardo S Mattos, Alperen Acemoglu, André Geraldes, Andrea Laborai, Andreas Schoob, Brahim Tamadazte, Brian Davies, Bruno Wacogne, Christian Pieralli, Corina Barbalata and 23 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in robotics and AI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Light in the Larynx: a Miniaturized Robotic Optical Fiber for In-office Laser Surgery of the Vocal Folds.Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 16 institutions in 6 countries.

Leonardo S MattosIstituto Italiano di Tecnologia, Genoa, Italy.
Alperen AcemogluIstituto Italiano di Tecnologia, Genoa, Italy.
André GeraldesIstituto Italiano di Tecnologia, Genoa, Italy.
Andrea LaboraiDepartment of Otorhinolaryngology, Guglielmo da Saliceto Hospital, Piacenza, Italy.
Andreas SchoobYuanda Robotics GmbH, Hannover, Germany.
Brahim TamadazteInstitut des Systèmes Intelligents et de Robotique, Sorbonne Université, CNRS, Paris, France.
Brian DaviesImperial College London, London, United Kingdom.
Bruno WacogneFEMTO-ST Institute, Univ. Bourgogne Franche-Comte, CNRS, Besançon, France.
Christian PieralliFEMTO-ST Institute, Univ. Bourgogne Franche-Comte, CNRS, Besançon, France.
Corina BarbalataMechanical and Industrial Engineering Department, Louisiana State University, Baton Rouge, LA, United States.
Darwin G CaldwellIstituto Italiano di Tecnologia, Genoa, Italy.
Dennis KundratImperial College London, London, United Kingdom.
Diego PardoIstituto Italiano di Tecnologia, Genoa, Italy.
Edward GrantDepartment of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC, United States.
Francesco MoraClinica Otorinolaringoiatrica, IRCCS Policlinico San Martino, Genoa, Italy.
Giacinto BarresiIstituto Italiano di Tecnologia, Genoa, Italy.
Giorgio PerettiClinica Otorinolaringoiatrica, IRCCS Policlinico San Martino, Genoa, Italy.
Jesùs OrtizIstituto Italiano di Tecnologia, Genoa, Italy.
Kanty RabenorosoaFEMTO-ST Institute, Univ. Bourgogne Franche-Comte, CNRS, Besançon, France.
Laurent TavernierCentre Hospitalier Régional Universitaire, Besançon, France.
Lionel PazartCentre Hospitalier Régional Universitaire, Besançon, France.
Loris FicheraDepartment of Robotics Engineering, Worcester Polytechnic Institute, Worcester, MA, United States.
Luca GuastiniClinica Otorinolaringoiatrica, IRCCS Policlinico San Martino, Genoa, Italy.
Lüder A KahrsDepartment of Mathematical and Computational Sciences, University of Toronto, Mississauga, ON, Canada.
Micky RakotondrabeNational School of Engineering in Tarbes, University of Toulouse, Tarbes, France.
Nicolas AndreffFEMTO-ST Institute, Univ. Bourgogne Franche-Comte, CNRS, Besançon, France.
Nikhil DeshpandeIstituto Italiano di Tecnologia, Genoa, Italy.
Olivier GaiffeCentre Hospitalier Régional Universitaire, Besançon, France.
Rupert RenevierFEMTO-ST Institute, Univ. Bourgogne Franche-Comte, CNRS, Besançon, France.
Sara MocciaThe BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy.
Sergio LescanoFEMTO-ST Institute, Univ. Bourgogne Franche-Comte, CNRS, Besançon, France.
Tobias OrtmaierInstitute of Mechatronic Systems, Leibniz Universität Hannover, Garbsen, Germany.
Veronica PenzaIstituto Italiano di Tecnologia, Genoa, Italy.
Italian Institute of Technology · ITCentre Hospitalier Universitaire de Besançon · FRCentre National de la Recherche Scientifique · FRUniversity of Genoa · ITFranche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies · FRImperial College London · GBÉcole Nationale d'Ingénieurs de Tarbes · FRGuglielmo da Saliceto Hospital · ITLeibniz University Hannover · DELouisiana State University · USNorth Carolina State University · USScuola Superiore Sant'Anna · ITSorbonne Université · FRUniversité Bourgogne Franche-Comté · FRUniversity of Toronto · CAWorcester Polytechnic Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laser microsurgery is the current gold standard surgical technique for the treatment of selected diseases in delicate organs such as the larynx. However, the operations require large surgical expertise and dexterity, and face significant limitations imposed by available technology, such as the requirement for direct line of sight to the surgical field, restricted access, and direct manual control of the surgical instruments. To change this status quo, the European project μRALP pioneered research towards a complete redesign of current laser microsurgery systems, focusing on the development of robotic micro-technologies to enable endoscopic operations. This has fostered awareness and interest in this field, which presents a unique set of needs, requirements and constraints, leading to research and technological developments beyond μRALP and its research consortium. This paper reviews the achievements and key contributions of such research, providing an overview of the current state of the art in robot-assisted endoscopic laser microsurgery. The primary target application considered is phonomicrosurgery, which is a representative use case involving highly challenging microsurgical techniques for the treatment of glottic diseases. The paper starts by presenting the motivations and rationale for endoscopic laser microsurgery, which leads to the introduction of robotics as an enabling technology for improved surgical field accessibility, visualization and management. Then, research goals, achievements, and current state of different technologies that can build-up to an effective robotic system for endoscopic laser microsurgery are presented. This includes research in micro-robotic laser steering, flexible robotic endoscopes, augmented imaging, assistive surgeon-robot interfaces, and cognitive surgical systems. Innovations in each of these areas are shown to provide sizable progress towards more precise, safer and higher quality endoscopic laser microsurgeries. Yet, major impact is really expected from the full integration of such individual contributions into a complete clinical surgical robotic system, as illustrated in the end of this paper with a description of preliminary cadaver trials conducted with the integrated μRALP system. Overall, the contribution of this paper lays in outlining the current state of the art and open challenges in the area of robot-assisted endoscopic laser microsurgery, which has important clinical applications even beyond laryngology.

Indexed as

augmented realitycancer imagingcognitive surgical systemcomputer-assisted surgeryflexible robotic endoscopelaser microsurgerymicro-robotsurgeon-robot interface

Identifiers

PMID34568434
PMCPMC8455830
OpenAlexW3196907567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.