Evidence map›Paper›PMID 34568424›Full record

ArticleFrontiers in molecular biosciences2021

Phylogenetic Comparison and Splicing Analysis of the U1 snRNP-specific Protein U1C in Eukaryotes.

Kai-Lu Zhang, Jian-Li Zhou, Jing-Fang Yang, Yu-Zhen Zhao, Debatosh Das, Ge-Fei Hao, Caie Wu, Jianhua Zhang, Fu-Yuan Zhu, Mo-Xian Chen and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Kai-Lu ZhangDivision of Gastroenterology, Shenzhen Children's Hospital, Shenzhen, China.
Jian-Li ZhouDivision of Gastroenterology, Shenzhen Children's Hospital, Shenzhen, China.
Jing-Fang YangKey Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China.
Yu-Zhen ZhaoDivision of Gastroenterology, Shenzhen Children's Hospital, Shenzhen, China.
Debatosh DasDepartment of Biology, Hong Kong Baptist University, and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, SAR China.
Ge-Fei HaoKey Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China.
Caie WuCollege of Light Industry and Food Engineering, Nanjing Forestry University, Jiangsu, China.
Jianhua ZhangDepartment of Biology, Hong Kong Baptist University, and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, SAR China.
Fu-Yuan ZhuCo-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Nanjing Forestry University, Nanjing, China.
Mo-Xian ChenCo-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Nanjing Forestry University, Nanjing, China.
Shao-Ming ZhouDivision of Gastroenterology, Shenzhen Children's Hospital, Shenzhen, China.
Shenzhen Children's Hospital · CNNanjing Forestry University · CNCentral China Normal University · CNChinese University of Hong Kong · CNHong Kong Baptist University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a pivotal regulator of 5' splice site recognition, U1 small nuclear ribonucleoprotein (U1 snRNP)-specific protein C (U1C) regulates pre-mRNA splicing by interacting with other components of the U1 snRNP complex. Previous studies have shown that U1 snRNP and its components are linked to a variety of diseases, including cancer. However, the phylogenetic relationships and expression profiles of U1C have not been studied systematically. To this end, we identified a total of 110 animal

Indexed as

alternative splicinggene expressionphylogeneticssplice siteU1-snRNP

Identifiers

PMID34568424
PMCPMC8458698
OpenAlexW3121030761

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.