Evidence map›Paper›PMID 34568295›Full record

ArticleFrontiers in bioengineering and biotechnology2021

3D Poly(Lactic Acid) Scaffolds Promote Different Behaviors on Endothelial Progenitors and Adipose-Derived Stromal Cells in Comparison With Standard 2D Cultures.

Giuliana Biagini, Alexandra Cristina Senegaglia, Tarciso Pereira, Lucas Freitas Berti, Bruna Hilzendeger Marcon, Marco Augusto Stimamiglio

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  12. Advancing bovineFrontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Giuliana BiaginiLaboratório de Biologia Básica de Células-Tronco, Instituto Carlos Chagas, Fiocruz Paraná, Curitiba, Brazil.
Alexandra Cristina SenegagliaNúcleo de Tecnologia Celular, Escola de Medicina, Pontifícia Universidade Católica Do Paraná, Curitiba, Brazil.
Tarciso PereiraDepartment of Mechanical Engineering, Post Graduate Program in Biomedical Engineering, Universidade Tecnológica Federal do Paraná, Curitiba, Brazil.
Lucas Freitas BertiDepartment of Mechanical Engineering, Post Graduate Program in Biomedical Engineering, Universidade Tecnológica Federal do Paraná, Curitiba, Brazil.
Bruna Hilzendeger MarconLaboratório de Biologia Básica de Células-Tronco, Instituto Carlos Chagas, Fiocruz Paraná, Curitiba, Brazil.
Marco Augusto StimamiglioLaboratório de Biologia Básica de Células-Tronco, Instituto Carlos Chagas, Fiocruz Paraná, Curitiba, Brazil.
Fundação Carlos Chagas · BRUniversidade Tecnológica Federal do Paraná · BRPontifícia Universidade Católica do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering is a branch of regenerative medicine, which comprises the combination of biomaterials, cells and other bioactive molecules to regenerate tissues. Biomaterial scaffolds act as substrate and as physical support for cells and they can also reproduce the extracellular matrix cues. Although tissue engineering applications in cellular therapy tend to focus on the use of specialized cells from particular tissues or stem cells, little attention has been paid to endothelial progenitors, an important cell type in tissue regeneration. We combined 3D printed poly(lactic acid) scaffolds comprising two different pore sizes with human adipose-derived stromal cells (hASCs) and expanded CD133

Indexed as

3D scaffoldexpanded CD133+ cellsmesenchymal stem cellspoly(lactic acid)–PLAtissue engineering

Identifiers

PMID34568295
PMCPMC8455839
OpenAlexW3196773691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.