Evidence map›Paper›PMID 34568279›Full record

ReviewFrontiers in chemistry2021

Review: Nanomaterials for Reactive Oxygen Species Detection and Monitoring in Biological Environments.

Gabriel T Huynh, Vidhishri Kesarwani, Julia A Walker, Jessica E Frith, Laurence Meagher, Simon R Corrie

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. CeOPlant molecular biology · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Application ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gabriel T HuynhDepartment of Chemical Engineering, Monash University, Clayton, VIC, Australia.
Vidhishri KesarwaniDepartment of Chemical Engineering, Monash University, Clayton, VIC, Australia.
Julia A WalkerDepartment of Chemical Engineering, Monash University, Clayton, VIC, Australia.
Jessica E FrithMonash Institute of Medical Engineering, Monash University, Clayton, VIC, Australia.
Laurence MeagherDepartment of Material Science and Engineering, Monash University, Clayton, VIC, Australia.
Simon R CorrieDepartment of Chemical Engineering, Monash University, Clayton, VIC, Australia.
Monash Medical Centre · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) and dissolved oxygen play key roles across many biological processes, and fluorescent stains and dyes are the primary tools used to quantify these species in vitro. However, spatio-temporal monitoring of ROS and dissolved oxygen in biological systems are challenging due to issues including poor photostability, lack of reversibility, and rapid off-site diffusion. In particular, ROS monitoring is hindered by the short lifetime of ROS molecules and their low abundance. The combination of nanomaterials and fluorescent detection has led to new opportunities for development of imaging probes, sensors, and theranostic products, because the scaffolds lead to improved optical properties, tuneable interactions with cells and media, and ratiometric sensing robust to environmental drift. In this review, we aim to critically assess and highlight recent development in nanosensors and nanomaterials used for the detection of oxygen and ROS in biological systems, and their future potential use as diagnosis tools.

Indexed as

bioimagingbiosensingnanomaterialsoxygenROS—reactive oxygen species

Identifiers

PMID34568279
PMCPMC8461210
OpenAlexW3199931538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.