Evidence map›Paper›PMID 34568057›Full record

ArticleFrontiers in oncology2021

Perioperative Outcome of Robotic Approach

Giulia Veronesi, Abbas El-Sayed Abbas, Piergiorgio Muriana, Rosalba Lembo, Edoardo Bottoni, Gianluca Perroni, Alberto Testori, Elisa Dieci, Charles T Bakhos, Shamus Car and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02804893 (Prospective, Randomized, Multicentric Study On Videothoracoscopic), which is not on this map. Cited by 63 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 6 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02804893 naunknown statusnot on this map

Prospective, Randomized, Multicentric Study On Videothoracoscopic (Vats) Vs Robotic Approach For Lobectomy Or Anatomical Segmentectomy In Patients Affected By Early Lung Cancer (ROMAN)

TypeinterventionalSponsorIstituto Clinico HumanitasRan2017 to 2023Enrolled300ConditionsLung CancerArmsVATS, RATS
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 6 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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  11. RoboticJournal of thoracic disease · 2026
    Article
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  15. Robotic Thoracic Surgery: Current Landscape and Future Directions.Interdisciplinary cardiovascular and thoracic surgery · 2026
    Review
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Giulia VeronesiDepartment of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Abbas El-Sayed AbbasDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Hospital, Philadelphia, PA, United States.
Piergiorgio MurianaDepartment of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Rosalba LemboDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Edoardo BottoniDivision of Thoracic and General Surgery, Humanitas Clinical and Research Center, Rozzano, Italy.
Gianluca PerroniDepartment of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alberto TestoriDivision of Thoracic and General Surgery, Humanitas Clinical and Research Center, Rozzano, Italy.
Elisa DieciDepartment of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Charles T BakhosDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Hospital, Philadelphia, PA, United States.
Shamus CarDivision of Thoracic Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, United States.
Luca LuzziThoracic Surgery Unit, Department of Medicine, Surgery and Neuro Sciences, Diagnostic Imaging, University of Siena, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Marco AlloisioDivision of Thoracic and General Surgery, Humanitas Clinical and Research Center, Rozzano, Italy.
Pierluigi NovellisDepartment of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Humanitas University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITTemple University Hospital · USVita-Salute San Raffaele University · ITAzienda Ospedaliera Universitaria Senese · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe report the results of the first prospective international randomized control trial to compare the perioperative outcome and surgical radicality of the robotic approach with those of traditional video-assisted surgery in the treatment of early-stage lung cancer.

methodsPatients with clinical stage T1-T2, N0-N1 non-small cell lung cancer (NSCLC) were randomly assigned to robotic-assisted thoracoscopic surgery (RATS) or video-assisted thoracic surgery (VATS) resection arms. The primary objective was the incidence of adverse events including complications and conversion to thoracotomy. The secondary objectives included extent of lymph node (LN) dissection and other indicators.

resultsThis trial was closed at 83 cases as the probability of concluding in favor of the robot arm for the primary outcome was null according to the observed trend. In this study, we report the results of the analysis conducted on the patients enrolled until trial suspension. Thirty-nine cases were randomized in the VATS arm and 38 in the robotic arm. Six patients were excluded from analysis. Despite finding no difference between the two arms in perioperative complications, conversions, duration of surgery, or duration of postoperative stay, a significantly greater degree of LN assessment by the robotic technique was observed in regards to the median number of sampled LN stations [6, interquartile range (IQR) 4-6

conclusionsThe results of this trial demonstrated that RATS was not superior to VATS considering the perioperative outcome for early-stage NSCLC, but the robotic approach allowed an improvement of LN dissection. Further studies are suggested to validate the results of this trial. CLINICAL

trial registrationclinicaltrials.gov, identifier NCT02804893.

Indexed as

non-small cell lung cancer (NSCLC)randomized studyrobotic surgerysurgeryVATS

Identifiers

PMID34568057
PMCPMC8458770
OpenAlexW3198082105

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.