Evidence map›Paper›PMID 34568055›Full record

ArticleFrontiers in oncology2021

Radiomic Evaluations of the Diagnostic Performance of DM, DBT, DCE MRI, DWI, and Their Combination for the Diagnosisof Breast Cancer.

Shuxian Niu, Xiaoyu Wang, Nannan Zhao, Guanyu Liu, Yangyang Kan, Yue Dong, E-Nuo Cui, Yahong Luo, Tao Yu, Xiran Jiang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shuxian NiuDepartment of Biomedical Engineering, School of Fundamental Sciences, China Medical University, Shenyang, China.
Xiaoyu WangLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Nannan ZhaoLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Guanyu LiuLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Yangyang KanLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Yue DongLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
E-Nuo CuiSchool of Computer Science and Engineering, Shenyang University, Shenyang, China.
Yahong LuoLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Tao YuLiaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.
Xiran JiangDepartment of Biomedical Engineering, School of Fundamental Sciences, China Medical University, Shenyang, China.
China Medical University · CNLiaoning Cancer Hospital & Institute · CNShenyang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate digital mammography (DM), digital breast tomosynthesis (DBT), dynamic contrast-enhanced (DCE), and diffusion-weighted (DW) MRI, individually and combined, for the values in the diagnosis of breast cancer, and propose a visualized clinical-radiomics nomogram for potential clinical uses.

methodsA total of 120 patients were enrolled between September 2017 and July 2018, all underwent preoperative DM, DBT, DCE, and DWI scans. Radiomics features were extracted and selected using the least absolute shrinkage and selection operator (LASSO) regression. A radiomics nomogram was constructed integrating the radiomics signature and important clinical predictors, and assessed with the receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA).

resultsThe radiomics signature derived from DBT plus DM generated a lower area under the ROC curve (AUC) and sensitivity, but a higher specificity compared with that from DCE plus DWI. The nomogram integrating the combined radiomics signature, age, and menstruation status achieved the best diagnostic performance in the training (AUCs, nomogram

conclusionsThe DBT plus DM provided a lower AUC and sensitivity, but a higher specificity than DCE plus DWI for detecting breast cancer. The proposed clinical-radiomics nomogram has diagnostic advantages over each modality, and can be considered as an efficient tool for breast cancer screening.

Indexed as

breastmammographyMRInomogramradiomics

Identifiers

PMID34568055
PMCPMC8461299
OpenAlexW3200802852

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.