Evidence map›Paper›PMID 34567930›Full record

Review3 Biotech2021

Emerging roles of NAC transcription factor in medicinal plants: progress and prospects.

Ramesh Kumar, Shantanu Das, Madhvi Mishra, Debjani Roy Choudhury, Komal Sharma, Abha Kumari, Rakesh Singh

Open access · greenAbstract readReview
In one paragraph

Review in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Comparative transcriptomics of anthocyanin accumulation in the pericarp of pigmented purple corn.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  5. ComparativeFrontiers in plant science · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Genome-wide identification of the NAC family inFrontiers in plant science · 2024
    Article
  15. International journal of molecular sciences · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ramesh KumarDivision of Genomic Resources, ICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012 India.ORCID https://orcid.org/0000-0002-9083-1654
Shantanu DasDivision of Genomic Resources, ICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012 India.
Madhvi MishraDivision of Genomic Resources, ICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012 India.
Debjani Roy ChoudhuryDivision of Genomic Resources, ICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012 India.
Komal SharmaDepartment of Plant Molecular Biology, University of Delhi South Campus, New Delhi, 110021 India.
Abha KumariAmity Institute of Biotechnology, Amity University Uttar Pradesh, Uttar Pradesh, Noida, 201313 India.
Rakesh SinghDivision of Genomic Resources, ICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012 India.ORCID 0000-0001-7269-6420
National Bureau of Plant Genetic Resources · INAmity University · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcriptional factors act as mediators in regulating stress response in plants from signal perception to processing the directed gene expression. WRKY, MYB, AP2/ERF, etc. are some of the major families of transcription factors known to mediate stress mechanisms in plants by regulating the production of secondary metabolites. NAC domain-containing proteins are among these large transcription factors families in plants. These proteins play impulsive roles in plant growth, development, and various abiotic as well as biotic stresses. They are involved in regulating the different signaling pathways of plant hormones that direct a plant's immunity against pathogens, thereby affecting their immune responses. However, their role in stress regulation or defence mechanism in plants through the secondary metabolite biosynthesis pathway is studied for very few cases. Emerging concern over the requirement of medicinal plants for the production of biocompatible drugs and antibiotics, the study of these vast, affecting proteins should be focused to improve their qualitative and quantitative production further. In medicinal plants, phytochemicals and secondary metabolites are the major biochemicals that impose antimicrobial and other medicinal properties in these plants. This review compiles the NAC transcription factors reported in selected medicinal plants and their possible roles in different mechanisms. Further, the comprehensive understanding of the molecular mechanism, genetic engineering, and regulation responses of NAC TFs in medicinal plants, can lead to improvement in stress response, immunity, and production of usable secondary metabolites.

Indexed as

Andrographis paniculataGene expressionSecondary metaboliteSignal transductionTranscriptional regulation

Identifiers

PMID34567930
PMCPMC8418584
OpenAlexW3197778617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.