ArticleMicrosystems & nanoengineering2021
Wireless, battery-free, and fully implantable electrical neurostimulation in freely moving rodents.
Article in Microsystems & nanoengineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 75 citations in OpenAlex.
- Battery-free, fully wireless neurostimulation via radiative RF power transfer in freely behaving mice.Microsystems & nanoengineering · 2026Article
- Ultralight infrared-controlled wireless neuromodulation systems for freely behaving mice.Microsystems & nanoengineering · 2026Article
- Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence.Nature communications · 2026Article
- Neural mechanisms underlying intracortical microstimulation for sensory restoration.Nature biomedical engineering · 2026Review
- Article
- Battery-Free Dual-Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation.Advanced healthcare materials · 2025Article
- Wireless nonresonant stimulation of neurons on a magnetoelectric film surface.Science advances · 2025Article
- A closed loop fully automated wireless vagus nerve stimulation system.Scientific reports · 2025Article
- Chronic, Battery-Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Continuous operation of battery-free implants enables advanced fracture recovery monitoring.Science advances · 2025Article
- Bio-Inspired Ionic Sensors: Transforming Natural Mechanisms into Sensory Technologies.Nano-micro letters · 2025Review
- Wireless Modular Implantable Neural Device with One-touch Magnetic Assembly for Versatile Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A wearable deep brain stimulation system for behavioral studies in rodents.Frontiers in neuroscience · 2025Article
- A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice.Nature electronics · 2025Article
- A Wireless Bi-Directional Brain-Computer Interface Supporting Both Bluetooth and Wi-Fi Transmission.Micromachines · 2024Article
- Article
- A wireless, battery-free device for electrical neuromodulation of bladder contractions.Materials today. Bio · 2024Article
- Lead-free dual-frequency ultrasound implants for wireless, biphasic deep brain stimulation.Nature communications · 2024Article
- A Wireless Battery-Free Implant With Optical Telemetry for In Vivo Cortical Stimulation.IEEE sensors letters · 2024Article
- Motor Behavior Regulation of Rat Robots Using Integrated Electrodes Stimulated by Micro-Nervous System.Micromachines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Implantable deep brain stimulation (DBS) systems are utilized for clinical treatment of diseases such as Parkinson's disease and chronic pain. However, long-term efficacy of DBS is limited, and chronic neuroplastic changes and associated therapeutic mechanisms are not well understood. Fundamental and mechanistic investigation, typically accomplished in small animal models, is difficult because of the need for chronic stimulators that currently require either frequent handling of test subjects to charge battery-powered systems or specialized setups to manage tethers that restrict experimental paradigms and compromise insight. To overcome these challenges, we demonstrate a fully implantable, wireless, battery-free platform that allows for chronic DBS in rodents with the capability to control stimulation parameters digitally in real time. The devices are able to provide stimulation over a wide range of frequencies with biphasic pulses and constant voltage control via low-impedance, surface-engineered platinum electrodes. The devices utilize off-the-shelf components and feature the ability to customize electrodes to enable broad utility and rapid dissemination. Efficacy of the system is demonstrated with a readout of stimulation-evoked neural activity in vivo and chronic stimulation of the medial forebrain bundle in freely moving rats to evoke characteristic head motion for over 36 days.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.