ArticleMicrosystems & nanoengineering2020
Infrared neural stimulation and inhibition using an implantable silicon photonic microdevice.
Article in Microsystems & nanoengineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 53 citations in OpenAlex.
- Integrating neural decoding, memristive materials, and adaptive control frameworks for next-generation hippocampal memory prosthetics.iScience · 2026Review
- Local infrared stimulation modulates spontaneous cortical slow wave dynamics in anesthetized rats.Scientific reports · 2026Article
- Focal thalamic infrared neural stimulation propagates dynamical transformations in auditory cortex.Journal of neural engineering · 2025Article
- Article
- Simultaneous Detection of Neural Activity and Temperature in Photothermal Neural Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches.Cells · 2025Review
- High density laminar recordings reveal cell type and layer specific responses to infrared neural stimulation in the rat neocortex.Scientific reports · 2024Article
- Infrared neuroglial modulation of spinal locomotor networks.Scientific reports · 2024Article
- Article
- Neurophotonics: a comprehensive review, current challenges and future trends.Frontiers in neuroscience · 2024Review
- Selective Infrared Neural Inhibition Can Be Reproduced by Resistive Heating.Neuromodulation : journal of the International Neuromodulation Society · 2023Article
- Thermal neuromodulation using pulsed and continuous infrared illumination in a penicillin-induced acute epilepsy model.Scientific reports · 2023Article
- Emerging trends in the development of flexible optrode arrays for electrophysiology.APL bioengineering · 2023Review
- Closed-loop seizure modulation via extreme learning machine based extended state observer.Cognitive neurodynamics · 2023Article
- Soft monolithic infrared neural interface for simultaneous neurostimulation and electrophysiology.Light, science & applications · 2023Article
- Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons.eLife · 2023Article
- Macromolecular rate theory explains the temperature dependence of membrane conductance kinetics.Biophysical journal · 2023Article
- Commonly Overlooked Factors in Biocompatibility Studies of Neural Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Mapping whole brain effects of infrared neural stimulation with positron emission tomography.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- In Vivo Penetrating Microelectrodes for Brain Electrophysiology.Sensors (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain is one of the most temperature sensitive organs. Besides the fundamental role of temperature in cellular metabolism, thermal response of neuronal populations is also significant during the evolution of various neurodegenerative diseases. For such critical environmental factor, thorough mapping of cellular response to variations in temperature is desired in the living brain. So far, limited efforts have been made to create complex devices that are able to modulate temperature, and concurrently record multiple features of the stimulated region. In our work, the in vivo application of a multimodal photonic neural probe is demonstrated. Optical, thermal, and electrophysiological functions are monolithically integrated in a single device. The system facilitates spatial and temporal control of temperature distribution at high precision in the deep brain tissue through an embedded infrared waveguide, while it provides recording of the artefact-free electrical response of individual cells at multiple locations along the probe shaft. Spatial distribution of the optically induced temperature changes is evaluated through in vitro measurements and a validated multi-physical model. The operation of the multimodal microdevice is demonstrated in the rat neocortex and in the hippocampus to increase or suppress firing rate of stimulated neurons in a reversible manner using continuous wave infrared light (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.