Evidence map›Paper›PMID 34567651›Full record

ArticleMicrosystems & nanoengineering2020

Single-vesicle imaging quantifies calcium's regulation of nanoscale vesicle clustering mediated by α-synuclein.

Bin Cai, Jie Liu, Yunfei Zhao, Xiangyu Xu, Bing Bu, Dechang Li, Lei Zhang, Wei Dong, Baohua Ji, Jiajie Diao

Open access · goldAbstract read
In one paragraph

Article in Microsystems & nanoengineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Molecular Dynamics Simulation for Membrane Fusion.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Article
  5. Article
  6. The function of VAMP2 in mediating membrane fusion: An overview.Frontiers in molecular neuroscience · 2022
    Review
  7. Article
  8. "Janus-Faced" α-Synuclein: Role in Parkinson's Disease.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Bin Cai *Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 USA.
Jie Liu *Biomechanics and Biomaterials Laboratory, Department of Applied Mechanics, Beijing Institute of Technology, Beijing, 100081 China.
Yunfei Zhao *Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000 China.
Xiangyu XuBiomechanics and Biomaterials Laboratory, Department of Applied Mechanics, Beijing Institute of Technology, Beijing, 100081 China.
Bing BuInstitute of Biomedical Engineering and Health Sciences, Changzhou University, Changzhou, Jiangsu 213164 China.ORCID 0000-0002-8273-0984
Dechang LiInstitute of Applied Mechanics, Department of Engineering Mechanics, Zhejiang University, Hangzhou, 310027 China.ORCID 0000-0002-9528-6851
Lei ZhangKey Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter (Ministry of Education), School of Science, Xi'an Jiaotong University, Xi'an, 710049 China.
Wei DongKey Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000 China.
Baohua JiInstitute of Applied Mechanics, Department of Engineering Mechanics, Zhejiang University, Hangzhou, 310027 China.
Jiajie DiaoDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 USA.ORCID 0000-0003-4288-3203
Beijing Institute of Technology · CNSouthwest Medical University · CNUniversity of Cincinnati Medical Center · USBeijing Advanced Sciences and Innovation Center · CNChangzhou University · CNXi'an Jiaotong University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although numerous studies have shown that the protein α-synuclein (α-Syn) plays a central role in Parkinson's disease, dementia with Lewy bodies, and other neurodegenerative diseases, the protein's physiological function remains poorly understood. Furthermore, despite recent reports suggesting that, under the influence of Ca

Indexed as

BiosensorsOptical sensors

Identifiers

PMID34567651
PMCPMC8433175
OpenAlexW3037229480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.