Evidence map›Paper›PMID 34567646›Full record

ArticleMicrosystems & nanoengineering2020

Low sample volume origami-paper-based graphene-modified aptasensors for label-free electrochemical detection of cancer biomarker-EGFR.

Yang Wang, Shuai Sun, Jinping Luo, Ying Xiong, Tao Ming, Juntao Liu, Yuanyuan Ma, Shi Yan, Yue Yang, Zhugen Yang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Microsystems & nanoengineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 101 citations in OpenAlex.

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  19. Microfluidic Paper-based Device for Medicinal Diagnosis.Current topics in medicinal chemistry · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Yang WangState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, 100190 China.
Shuai SunState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, 100190 China.
Jinping LuoState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, 100190 China.
Ying XiongKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, 100142 China.
Tao MingState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, 100190 China.
Juntao LiuState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, 100190 China.
Yuanyuan MaKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, 100142 China.
Shi YanKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, 100142 China.
Yue YangKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, 100142 China.
Zhugen YangDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Oakfield Avenue, Glasgow, G12 8LT United Kingdom.
Julien ReboudDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Oakfield Avenue, Glasgow, G12 8LT United Kingdom.
Huabing YinDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Oakfield Avenue, Glasgow, G12 8LT United Kingdom.
Jonathan M CooperDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Oakfield Avenue, Glasgow, G12 8LT United Kingdom.
Xinxia CaiState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, 100190 China.ORCID 0000-0001-5997-7252
Chinese Academy of Sciences · CNPeking University · CNUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, an electrochemical paper-based aptasensor was fabricated for label-free and ultrasensitive detection of epidermal growth factor receptor (EGFR) by employing anti-EGFR aptamers as the bio-recognition element. The device used the concept of paper-folding, or origami, to serve as a valve between sample introduction and detection, so reducing sampling volumes and improving operation convenience. Amino-functionalized graphene (NH

Indexed as

BiosensorsMicrofluidicsNanoparticles

Identifiers

PMID34567646
PMCPMC8433370
OpenAlexW3024429986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.