ArticleChemical science2021
Ruthenium(ii)-catalyzed regioselective direct C4- and C5-diamidation of indoles and mechanistic studies.
Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 21 citations in OpenAlex.
- Ru(II)-Catalyzed Cascade Regioselective C-7 and C-8 Diamidation of Isoquinolinones Using Dioxazolones.Chemistry, an Asian journal · 2026Article
- Dioxazolones as electrophilic amide sources in copper-catalyzed and -mediated transformations.Beilstein journal of organic chemistry · 2025Review
- Ir(iii)/Ag(i)-catalyzed directly C-H amidation of arenes with OH-free hydroxyamides as amidating agents.RSC advances · 2024Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A ruthenium(ii)-catalyzed regioselective direct diamidation of 3-carbonylindoles at the C4- and C5-positions using various dioxazolones is described. This novel protocol allows for the effective installation of two amide groups on the benzene ring in indole. A remarkably broad substrate scope, excellent functional group tolerance, and mild reaction conditions are notable features of this protocol. Further explorations reveal that benzo[
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