Evidence map›Paper›PMID 34567434›Full record

ArticleWorld journal of radiology2021

Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients.

Fabiana Perrone, Maurizio Balbi, Chiara Casartelli, Sebastiano Buti, Gianluca Milanese, Nicola Sverzellati, Melissa Bersanelli

Open access · diamondAbstract read
In one paragraph

Article in World journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Fabiana PerroneMedical Oncology Unit, University Hospital of Parma, Parma 43126, Italy.
Maurizio BalbiDepartment of Surgical Sciences, Institute of Diagnostic and Interventional Radiology, University of Parma, Parma 43126, Italy.
Chiara CasartelliMedical Oncology Unit, University Hospital of Parma, Parma 43126, Italy.
Sebastiano ButiMedical Oncology Unit, University Hospital of Parma, Parma 43126, Italy.
Gianluca MilaneseDepartment of Surgical Sciences, Institute of Diagnostic and Interventional Radiology, University of Parma, Parma 43126, Italy.
Nicola SverzellatiDepartment of Surgical Sciences, Institute of Diagnostic and Interventional Radiology, University of Parma, Parma 43126, Italy.
Melissa BersanelliMedical Oncology Unit, University Hospital of Parma, Parma 43126, Italy.
University Hospitals Parma Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the several radiological features shared by coronavirus disease 2019 pneumonia and other infective or non-infective diseases with lung involvement, the differential diagnosis is often tricky, and no unequivocal tool exists to help the radiologist in the proper diagnosis. Computed tomography is considered the gold standard in detecting pulmonary illness caused by severe acute respiratory syndrome coronavirus 2.

aimTo conduct a systematic review including the available studies evaluating computed tomography similarities and discrepancies between coronavirus disease 2019 pneumonia and other pulmonary illness, then providing a discussion focus on cancer patients.

methodsUsing pertinent keywords, we performed a systematic review using PubMed to select relevant studies published until October 30, 2020.

resultsOf the identified 133 studies, 18 were eligible and included in this review.

conclusionGround-glass opacity and consolidations are the most common computed tomography lesions in coronavirus disease 2019 pneumonia and other respiratory diseases. Only two studies included cancer patients, and the differential diagnosis with early lung cancer and radiation pneumonitis was performed. A single lesion associated with pleural effusion and lymphadenopathies in lung cancer and the onset of the lesions in the radiation field in the case of radiation pneumonitis allowed the differential diagnosis. Nevertheless, the studies were heterogeneous, and the type and prevalence of lesions, distributions, morphology, evolution, and additional signs, together with epidemiological, clinical, and laboratory findings, are crucial to help in the differential diagnosis.

Indexed as

CancerComputed tomographyCOVID-19Differential diagnosisPneumoniaRadiological findings

Identifiers

PMID34567434
PMCPMC8422906
OpenAlexW3193334135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.