Evidence map›Paper›PMID 34567415›Full record

ReviewOxidative medicine and cellular longevity2021

The Positive Role and Mechanism of Herbal Medicine in Parkinson's Disease.

Rong Yin, Jie Xue, Yanfeng Tan, Chuantao Fang, Chunchun Hu, Qian Yang, Xinyu Mei, Dashi Qi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  11. Antioxidants (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Review
  14. Review
  15. TiOAdvances in neurobiology · 2023
    Review
  16. Article
  17. The Effects ofMedicina (Kaunas, Lithuania) · 2022
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rong Yin *Institute of Pediatrics, Department of Neonatology, Developmental and Behavioral Pediatric Department & Child Health Care Department, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Jie Xue *Center for Clinical Research and Translational Medicine, Department of Neurology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China.
Yanfeng TanInstitute of Pediatrics, Department of Neonatology, Developmental and Behavioral Pediatric Department & Child Health Care Department, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Chuantao FangTenth People's Hospital of Tongji University, Tongji University School of Medicine, Shanghai, China.
Chunchun HuInstitute of Pediatrics, Department of Neonatology, Developmental and Behavioral Pediatric Department & Child Health Care Department, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Qian YangInstitute of Pediatrics, Department of Neonatology, Developmental and Behavioral Pediatric Department & Child Health Care Department, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Xinyu MeiCenter for Clinical Research and Translational Medicine, Department of Neurology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-2637-795X
Dashi QiInstitute of Pediatrics, Department of Neonatology, Developmental and Behavioral Pediatric Department & Child Health Care Department, Children's Hospital of Fudan University, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-0614-7068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a complex neurodegenerative disease, manifested by the progressive functional impairment of the midbrain nigral dopaminergic neurons. Due to the unclear underlying pathogenesis, disease-modifying drugs for PD remain elusive. In Asia, such as in China and India, herbal medicines have been used in the treatment of neurodegenerative disease for thousands of years, which recently attracted considerable attention because of the development of curative drugs for PD. In this review, we first summarized the pathogenic factors of PD including protein aggregation, mitochondrial dysfunction, ion accumulation, neuroinflammation, and oxidative stress, and the related recent advances. Secondly, we summarized 32 Chinese herbal medicines (belonging to 24 genera, such as

Indexed as

AnimalsHerbal MedicineHumansNeuroprotective AgentsParkinson DiseasePhytotherapyNeuroprotective Agents

Identifiers

PMID34567415
PMCPMC8457986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.