Evidence map›Paper›PMID 34567251›Full record

ArticleEcancermedicalscience2021

Evaluation of oxidative markers in women with invasive cervical cancer in Lagos, Nigeria.

Juliet O Offor, Kehinde S Okunade, Bamidele A Iwalokun, Ayodeji A Oluwole, Rose I Anorlu

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Juliet O OfforDepartment of Obstetrics & Gynaecology, Federal Medical Centre, Jabi, Abuja FCT, Nigeria.
Kehinde S OkunadeDepartment of Obstetrics & Gynaecology, College of Medicine, University of Lagos, PMB 12003, Idi-Araba, Lagos, Nigeria.
Bamidele A IwalokunDepartment of Molecular Biology & Biotechnology, Nigerian Institute of Medical Research (NIMR), Yaba, Lagos, Nigeria.
Ayodeji A OluwoleDepartment of Obstetrics & Gynaecology, College of Medicine, University of Lagos, PMB 12003, Idi-Araba, Lagos, Nigeria.
Rose I AnorluDepartment of Obstetrics & Gynaecology, College of Medicine, University of Lagos, PMB 12003, Idi-Araba, Lagos, Nigeria.
University of Lagos · NGFederal Medical Centre · NGNigerian Institute of Medical Research · NG

Funding

Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
Building Research And Innovation in Nigeria's Science - (BRAINS)D43TW010134 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF LAGOS · PI OGUNSOLA, FOLASADE TOLULOPE · 2015 to 2020
$3.2M
Nigeria HIV Research Training ProgramD43TW010934 · FIC · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2019 to 2026
$2.4M
FIC NIH HHS D43 TW010134FIC NIH HHS D43 TW010543FIC NIH HHS D43 TW010934NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

Epidemiological studies have showed that low levels of antioxidants induce the generation of free radicals leading to DNA damage and further mutations seen in cancer. This study evaluated the effects of oxidative markers on the occurrence and severity of cervical cancer at the Lagos University Teaching Hospital. This was an analytical cross-sectional study carried out among women with histological diagnosis of invasive cervical cancer and their healthy cancer-free comparison group. Venous blood samples were collected from each participant for measurements of antioxidants (erythrocyte glutathione and vitamin C) and malondialdehyde (a marker of lipid peroxidation). Descriptive statistics were carried out for relevant demographic and clinical data. Associations between continuous variables were tested using the independent sample t-test or the analysis of variance for normally distributed data or the Mann-Whitney U test for skewed data, whereas categorical variables were compared using the χ

Indexed as

carcinomacervixglutathionemalondialdehydevitamin C

Identifiers

PMID34567251
PMCPMC8426022
OpenAlexW3179988345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.