Evidence map›Paper›PMID 34567180›Full record

ArticleIranian journal of pharmaceutical research : IJPR2021

Synthesis, Antimicrobial Activity, and Molecular Docking Studies of Aminoguanidine Derivatives Containing an Acylhydrazone Moiety.

Xiaodong Yao, Hongmei Hu, Shiben Wang, Wenhao Zhao, Mingxia Song, Qiugui Zhou

Abstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Computational andBiomedical reports · 2024
    Article
  4. Acylhydrazones and Their Biological Activity: A Review.Molecules (Basel, Switzerland) · 2022
    Review
  5. A Review of the Biological Activity of Amidrazone Derivatives.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaodong YaoJiangxi Institute of Biological Products Inc, Ji'an , 343009, Jiangxi, China.
Hongmei HuMedical College, Jinggangshan University, Ji'an , 343009, Jiangxi, China.
Shiben WangSchool of Pharmacy, Liaocheng University, LiaoCheng, 252059, Shandong, China.
Wenhao ZhaoMedical College, Jinggangshan University, Ji'an , 343009, Jiangxi, China.
Mingxia SongMedical College, Jinggangshan University, Ji'an , 343009, Jiangxi, China.
Qiugui ZhouMedical College, Jinggangshan University, Ji'an , 343009, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of aminoguanidine derivatives containing an acylhydrazone moiety was designed based on combination principles to find new antibacterial agents with wide spectra and high activities. The synthesized compounds were characterized by spectral methods and screened for their antibacterial activity. The results showed that several compounds provided great antimicrobial activities against Gram-positive bacteria (including the multidrug-resistant clinical isolates). Especially, this series of compounds presented high potency against

Indexed as

AcylhydrazoneAminoguanidineAntibacterial activityDrug-resistance bacterialMolecular docking

Identifiers

PMID34567180
PMCPMC8457745

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.