Evidence map›Paper›PMID 34567059›Full record

ArticleFrontiers in genetics2021

Identification of a miRNA-mRNA Regulatory Networks in Placental Tissue Associated With Tibetan High Altitude Adaptation.

Noryung Tenzing, Martha Tissot van Patot, Huifang Liu, Qiying Xu, Juanli Liu, Zhuoya Wang, Yanjun Wang, Tana Wuren, Ri-Li Ge

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The uteroplacental circulation at high altitude: adaptation and maladaptation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  5. Placental Adaptation to Hypoxia: The Case of High-Altitude Pregnancies.International journal of environmental research and public health · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Noryung TenzingResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Martha Tissot van PatotIndependent Researcher, Fort Collins, CO, United States.
Huifang LiuResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Qiying XuResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Juanli LiuResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Zhuoya WangResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Yanjun WangResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Tana WurenResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Ri-Li GeResearch Center for High Altitude Medicine, Qinghai University, Xining, China.
Qinghai University Affiliated Hospital · CNQinghai University · CNQinghai Provincial Peoples Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Tibetan population has lived and successfully reproduced at high altitude for many generations. Studies have shown that Tibetans have various mechanisms for protection against high-altitude hypoxia, which are probably due, at least in part, to placental adaptation. However, comprehensive

Indexed as

ER stresshigh altitudehypoxiaplacentaTibetan

Identifiers

PMID34567059
PMCPMC8460760
OpenAlexW3200353035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.