Evidence map›Paper›PMID 34566983›Full record

ArticleFrontiers in immunology2021

Presence of Anti-Thyroid Antibodies Correlate to Worse Outcome of Anti-NMDAR Encephalitis.

Zhongyun Chen, Yan Zhang, Lili Cui, Huijin Huang, Weibi Chen, Yingying Su

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhongyun ChenDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yan ZhangDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Lili CuiDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Huijin HuangDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Weibi ChenDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yingying SuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the characteristics and prognosis of anti-NMDAR encephalitis with the prevalence of anti-thyroid antibodies (ATAbs). Methods: The clinical data of anti-NMDAR encephalitis patients admitted to Xuanwu Hospital from January 2012 to August 2018 was prospectively analyzed, and the patients were followed up for 24 months. Results: A total of 120 patients were enrolled, of which 34.2% (41/120) were positive for ATAbs. The antibodies were more frequent in patients with severe disease compared to the non-severe group (51.4% Conclusion: ATAbs are prevalent in patients with anti-NMDAR encephalitis, especially in severe cases, and correlate with poor prognosis and impaired short-term neurological recovery.

Indexed as

AdolescentAdultAnti-N-Methyl-D-Aspartate Receptor EncephalitisAutoantibodiesFemaleHumansImmunoglobulins, IntravenousLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrognosisProspective StudiesRisk FactorsThyroglobulinanti-thyroglobulinAutoantibodiesImmunoglobulins, IntravenousThyroglobulinanti-N-methyl-D-aspartate receptor encephalitisanti-thyroglobulin antibodyanti-thyroperoxidase antibodycritically illoutcome

Identifiers

PMID34566983
PMCPMC8456002

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.