Evidence map›Paper›PMID 34566971›Full record

ArticleFrontiers in immunology2021

The Tec Kinase Itk Integrates Naïve T Cell Migration and

Flavian Thelen, Stefanie Wissmann, Nora Ruef, Jens V Stein

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Expression of WNT10A in papillary thyroid carcinoma and its effect on cell proliferation, invasion, and metastasis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  3. Inhibitory Effects ofPlants (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Insights from DOCK2 in cell function and pathophysiology.Frontiers in molecular biosciences · 2022
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Flavian ThelenDepartment of Medical Oncology and Hematology, University of Zürich and University Hospital Zürich, Zürich, Switzerland.
Stefanie WissmannDepartment of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
Nora RuefDepartment of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
Jens V SteinDepartment of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
University of Fribourg · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naïve T cells (T

Indexed as

HomeostasisAnimalsBiomarkersCell MovementChemokine CCL21CytokinesLymph NodesLymphocyte ActivationMiceProtein-Tyrosine KinasesSignal TransductionT-LymphocytesBiomarkersChemokine CCL21Cytokinesemt protein-tyrosine kinaseProtein-Tyrosine KinasesCCL21/CCR7 axischemokineintravital 2-photon microscopysignal transductionT cell traffickingTec kinase

Identifiers

PMID34566971
PMCPMC8458560
OpenAlexW3199854824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.