Evidence map›Paper›PMID 34566902›Full record

ArticleFrontiers in microbiology2021

Biochemical Characterization of a Novel Redox-Regulated Metacaspase in a Marine Diatom.

Shiri Graff van Creveld, Shifra Ben-Dor, Avia Mizrachi, Uria Alcolombri, Amanda Hopes, Thomas Mock, Shilo Rosenwasser, Assaf Vardi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Differential Expression of Stress Adaptation Genes in a DiatomInternational journal of molecular sciences · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Structure-function study of a CaProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Shiri Graff van CreveldDepartment of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.
Shifra Ben-DorDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Avia MizrachiDepartment of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.
Uria AlcolombriDepartment of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.
Amanda HopesSchool of Environmental Sciences, University of East Anglia, Norwich, United Kingdom.
Thomas MockSchool of Environmental Sciences, University of East Anglia, Norwich, United Kingdom.
Shilo RosenwasserRobert H. Smith Faculty of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Jerusalem, Israel.
Assaf VardiDepartment of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.
Weizmann Institute of Science · ILUniversity of East Anglia · GBÉcole Polytechnique Fédérale de Lausanne · CHHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Programmed cell death (PCD) in marine microalgae was suggested to be one of the mechanisms that facilitates bloom demise, yet its molecular components in phytoplankton are unknown. Phytoplankton are completely lacking any of the canonical components of PCD, such as caspases, but possess metacaspases. Metacaspases were shown to regulate PCD in plants and some protists, but their roles in algae and other organisms are still elusive. Here, we identified and biochemically characterized a type III metacaspase from the model diatom

Indexed as

diatominfochemicalsmetacaspasePhaeodactylum tricornutumphytoplanktonprogrammed cell deathreactive oxygen speciesredox-regulation

Identifiers

PMID34566902
PMCPMC8455989
OpenAlexW3197193580

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.