Evidence map›Paper›PMID 34566868›Full record

ArticleFrontiers in neurology2021

Cortical and Subcortical Network Dysfunction in a Female Patient With

Maria Cristina Cioclu, Antonietta Coppola, Manuela Tondelli, Anna Elisabetta Vaudano, Giada Giovannini, S Krithika, Michele Iacomino, Federico Zara, Sanjay M Sisodiya, Stefano Meletti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Life (Basel, Switzerland) · 2025
    Article
  4. Article
  5. X-Linked Epilepsies: A Narrative Review.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Maria Cristina CiocluDepartment of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.
Antonietta CoppolaDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy.
Manuela TondelliNeurology Unit, OCB Hospital, Azienda Ospedaliera Universitaria di Modena, Modena, Italy.
Anna Elisabetta VaudanoNeurology Unit, OCB Hospital, Azienda Ospedaliera Universitaria di Modena, Modena, Italy.
Giada GiovanniniDepartment of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.
S KrithikaDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.
Michele IacominoUnit of Medical Genetics, IRCCS Giannina Gaslini Institute, Genova, Italy.
Federico ZaraUnit of Medical Genetics, IRCCS Giannina Gaslini Institute, Genova, Italy.
Sanjay M SisodiyaDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.
Stefano MelettiDepartment of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.
Policlinico di Modena · ITFederico II University Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Giannina Gaslini · ITNational Hospital for Neurology and Neurosurgery · GBUniversity College London · GBUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The developmental and epileptic encephalopathies (DEE) are the most severe group of epilepsies. Recently,

Indexed as

developmental and epileptic encephalopathyepilepsyeyelid myoclonia with absencesfMRINEXMIFnon convulsive status epilepticus

Identifiers

PMID34566868
PMCPMC8459922
OpenAlexW3198060961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.