ArticleFrontiers in neurology2021
Age-at-Injury Determines the Extent of Long-Term Neuropathology and Microgliosis After a Diffuse Brain Injury in Male Rats.
Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Pediatric traumatic brain injury elicits acute neuroinflammation and long-term changes in social, cognitive, and decision-making behaviors in male and female rats.bioRxiv : the preprint server for biology · 2026Article
- PRECISE TBI Model Catalog: Increasing Accessibility and Reproducibility in TBI research.bioRxiv : the preprint server for biology · 2026Article
- Advances and challenges in experimental models of posttraumatic epilepsy for therapeutic interventions.Pharmacological reviews · 2025Review
- Integrative Diagnostic and Prognostic Paradigms in Diffuse Axonal Injury: Insights from Clinical, Histopathological, Biomolecular, Radiological, and AI-Based Perspectives.International journal of molecular sciences · 2025Review
- Adverse impact of female reproductive signaling on age-dependent neurodegeneration after mild head trauma ineLife · 2024Article
- Quantifying microglial morphology: an insight into function.Clinical and experimental immunology · 2024Review
- Methanol extract ofFrontiers in pharmacology · 2024Article
- Diffuse traumatic brain injury substantially alters plasma growth hormone in the juvenile rat.The Journal of endocrinology · 2024Article
- Identifying the Phenotypes of Diffuse Axonal Injury Following Traumatic Brain Injury.Brain sciences · 2023Review
- Do astrocytes act as immune cells after pediatric TBI?Neurobiology of disease · 2023Review
- Spinal cord injury leads to more neurodegeneration in the hippocampus of aged male rats compared to young rats.Experimental brain research · 2023Article
- Article
- Review
- Amelioration of Brain Damage after Treatment with the Methanolic Extract ofPharmaceutics · 2022Article
- Age-At-Injury Influences the Glial Response to Traumatic Brain Injury in the Cortex of Male Juvenile Rats.Frontiers in neurology · 2021Article
- A Levee to the Flood: Pre-injury Neuroinflammation and Immune Stress Influence Traumatic Brain Injury Outcome.Frontiers in aging neuroscience · 2021Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic brain injury (TBI) can occur at any age, from youth to the elderly, and its contribution to age-related neuropathology remains unknown. Few studies have investigated the relationship between age-at-injury and pathophysiology at a discrete biological age. In this study, we report the immunohistochemical analysis of naïve rat brains compared to those subjected to diffuse TBI by midline fluid percussion injury (mFPI) at post-natal day (PND) 17, PND35, 2-, 4-, or 6-months of age. All brains were collected when rats were 10-months of age (
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