ArticleFrontiers in neurology2021
Historical Patterns of Diagnosis, Treatments, and Outcome of Epilepsy Associated With Tuberous Sclerosis Complex: Results From TOSCA Registry.
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In one paragraph
Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Burden of illness in tuberous sclerosis complex-associated epilepsy: a systematic literature review of epidemiology, health-related quality of life, costs and resource use.Orphanet journal of rare diseases · 2025Pooled it
- Features and management of kidney manifestations of tuberous sclerosis complex: a real-world study in a Brazilian patient cohort.BMC nephrology · 2026Observational
- Tuberous sclerosis complex.Nature reviews. Disease primers · 2026Review
- Old Lesions and New Targets: sEEG-Identified Onsets in Traditionally Inoperable Epilepsy Lesions and Associated Surgical Outcomes.Pediatric neurosurgery · 2026Review
- Genetic screening of tuberous sclerosis complex in Sicily with a focus on neurological manifestations.Scientific reports · 2025Article
- An interpretable machine learning approach for predicting drug-resistant epilepsy in children with tuberous sclerosis complex.Frontiers in neurology · 2025Article
- Radiosensitivity in individuals with tuberous sclerosis complex.Discover oncology · 2024Article
- Screening for biomarkers of tuberous sclerosis complex-associated epilepsy: a bioinformatics analysis.Translational pediatrics · 2024Article
- Article
- A single-center observational study on long-term neurodevelopmental outcomes in children with tuberous sclerosis complex.Orphanet journal of rare diseases · 2023Observational
- Epileptogenic Tubers Are Associated with Increased Kurtosis of Susceptibility Values: A Combined Quantitative Susceptibility Mapping and Stereoelectroencephalography Pilot Study.AJNR. American journal of neuroradiology · 2023Article
- Epileptogenesis in tuberous sclerosis complex-related developmental and epileptic encephalopathy.Brain : a journal of neurology · 2023Review
- Demographic characteristics and clinical presentation of infants with infantile epileptic spasms syndrome and their response to therapy: Data from Sri Lanka Infantile Spasms Registry.Annals of the Child Neurology Society · 2023Article
- Clinical seizure semiology is subtle and identification of seizures by parents is unreliable in infants with tuberous sclerosis complex.Epilepsia · 2023Article
- Modeling genetic mosaicism of the mammalian target of rapamycin pathway in the cerebral cortex.Frontiers in mammal science · 2023Article
- GENE TARGET: A framework for evaluating Mendelian neurodevelopmental disorders for gene therapy.Molecular therapy. Methods & clinical development · 2022Review
- Tuberous Sclerosis Complex Patients' Needs and Difficulties-Results of TAND Questionnaire Analysis in Polish Adult Population.Journal of clinical medicine · 2022Article
- Monitoring and Managing Patients with Tuberous Sclerosis Complex: Current State of Knowledge.Journal of multidisciplinary healthcare · 2022Review
- Vigabatrin in Epilepsy Related to TSC: Does it PREVeNT AND OR (EPI) STOP Seizures OR… Do We Need Some More STEPS as VI RAP?Epilepsy currentsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 20 institutions in 18 countries.
Rima NabboutDepartment of Pediatric Neurology, Reference Centre for Rare Epilepsies, Member of EPICARE Network, Necker Enfants Malades Hospital, Université de Paris, Institut Imagine (Inserm U1163), Paris, France.
Elena BelousovaDepartment of Pediatrics, Research and Clinical Institute of Pediatrics, Pirogov Russian National Research Medical University, Moscow, Russia.
Mirjana P BenedikDepartment of Pediatric Neurology, SPS Paediatric Clinic, Ljubljana, Slovenia.
Tom CarterTuberous Sclerosis Association, Nottingham, United Kingdom.
Vincent CottinDepartment of Respiratory Medicine, Hôpital Louis Pradel, Claude Bernard University Lyon 1, Lyon, France.
Paolo CuratoloDepartment of Neurology, Tor Vergata University Hospital, Rome, Italy.
Maria DahlinNeuropediatric Unit, Karolinska University Hospital, Stockholm, Sweden.
Lisa D'AmatoNovartis Farma S.p.A., Origgio, Italy.
Guillaume Beaure d'AugèresTuberous Sclerosis Association of Bourneville, Gradignan, France.
Petrus J de VriesDivision of Child and Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
José C FerreiraNeurologia Pediátrica, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Martha FeuchtDepartment of Pediatrics and Adolescent Medicine, Medical University of Vienna (Affiliated Partner of the ERN EpiCARE), Vienna, Austria.
Carla FladrowskiTuberous Sclerosis Association ONLUS, Milan, Italy.
Christoph HertzbergZentrum für Sozialpädiatrie und Neuropädiatrie (DBZ), Vivantes Hospital Neukoelln, Berlin, Germany.
Sergiusz JozwiakDepartment of Child Neurology, Medical University of Warsaw, Warsaw, Poland.
John A LawsonDepartment of Neurology, The Tuberous Sclerosis Multidisciplinary Management Clinic, Sydney Children's Hospital, Randwick, NSW, Australia.
Alfons MacayaDepartment of Pediatric Neurology, Vall d'Hebron University Hospital, Barcelona, Spain.
Ruben MarquesNovartis Farma S.p.A., Origgio, Italy.
Finbar O'CallaghanPaediatric Neuroscience, Institute of Child Health, University College London, London, United Kingdom.
Jiong QinDepartment of Pediatrics, Peking University People's Hospital, Beijing, China.
Matthias SauterKlinkverbund Allgäu gGmbH Hospital, Kempten, Germany.
Seema ShahNovartis Healthcare Pvt. Ltd., Hyderabad, India.
Yukitoshi TakahashiNational Epilepsy Center, National Hospital Organization (NHO), Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan.
Renaud TouraineDepartment of Genetics, Centre Hospitalier Universitaire (CHU)-Hôpital Nord, Saint Etienne, France.
Sotiris YouroukosFirst Department of Paediatrics, Athens University Medical School, St. Sophia Children's Hospital, Athens, Greece.
Bernard ZonnenbergDepartment of Internal Medicine, University Medical Center, Utrecht, Netherlands.
Anna C JansenPediatric Neurology Unit, Department of Pediatrics, UZ Brussel Vrije Universiteit Brussel (VUB), Brussels, Belgium.
J Chris KingswoodCardiology Clinical Academic Group, Molecular and Clinical Sciences Research Centre, St Georges University of London, London, United Kingdom.
Centro Hospitalar de Lisboa Ocidental · PTChildren's Hospital Agia Sophia · GRHôpital Nord · FRKarolinska University Hospital · SEKlinikverbund Südwest · DEMedical University of Vienna · ATMedical University of Warsaw · PLNational Epilepsy Center · JPNovartis (India) · INNovartis (Italy) · ITPeking University · CNPirogov Russian National Research Medical University · RUSt George's, University of London · GBSydney Children's Hospital · AUTuberous Sclerosis Association · GBUniversidad de León · ESUniversité Claude Bernard Lyon 1 · FRUniversité Paris Cité · FRUniversity College London · GBUniversity Medical Center Utrecht · NL
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
epilepsyregistryTOSCATSCtuberous sclerosis complex
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What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.