Evidence map›Paper›PMID 34566427›Full record

ReviewInternational journal of general medicine2021

An Update in Our Understanding of the Relationships Between Gene Polymorphisms and Chemotherapy-Induced Nausea and Vomiting.

Yilan Jin, Xiaorong Li, Caihong Jiang, Jun Zhao, Guang Liu, Hui Li, Gaowa Jin, Quanfu Li

Abstract readReview
In one paragraph

Review in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yilan Jin *Department of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Xiaorong Li *Department of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Caihong Jiang *Department of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Jun ZhaoDepartment of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Guang LiuDepartment of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Hui LiDepartment of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Gaowa JinDepartment of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.
Quanfu LiDepartment of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occurrence and severity of chemotherapy-induced nausea and vomiting (CINV) are influenced by many factors; this includes therapeutic factors, such as the dose, administration mode, and chemotherapeutic agent emetogenicity, as well as patient-related risk factors, such as the gender, age, alcohol consumption history, and anxiety level. However, these factors cannot fully explain the individual CINV differences. In recent years, the correlation between gene polymorphism and CINV has been a hot research topic; the present paper reviews current research on CINV-related gene polymorphisms, and the results indicate that the use of gene polymorphism for the optimization of CINV efficacy is of important clinical significance.

Indexed as

antiemeticchemotherapy-induced nausea and vomitinggene polymorphismsprevention and treatment

Identifiers

PMID34566427
PMCPMC8458022

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.