Evidence map›Paper›PMID 34566340›Full record

ArticleVeterinary world2021

Antibacterial activity of clove (

Elgio Venanda Ginting, Endah Retnaningrum, Dyah Ayu Widiasih

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  8. Frontiers in microbiology · 2025
    Review
  9. Article
  10. Anti-quorum sensing activity of essential oils against multidrug-resistant Klebsiella pneumoniae: a novel approach to control bacterial virulence.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  11. Article
  12. Article
  13. Plant-Origin Components: New Players to Combat Antibiotic Resistance inInternational journal of molecular sciences · 2024
    Review
  14. Article
  15. Article
  16. Anti-Biofilm Potential ofAdvanced biomedical research · 2023
    Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elgio Venanda GintingFaculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Endah RetnaningrumFaculty of Biology, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Dyah Ayu WidiasihFaculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Universitas Gadjah Mada · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimExtended-spectrum β-lactamase (ESBL) is an enzyme produced by the family of MATERIALS AND

methodsThe antibacterial activity of clove and cinnamon essential oils was tested against three strains of tested bacteria using the disk diffusion method. The minimum inhibitory concentration (MIC) of clove and cinnamon essential oils was determined using the broth microdilution method. The minimumbactericidal concentration (MBC) was determined using the MIC. Morphological changes on each tested bacteria were observed through scanning electron microscopy (SEM).

resultsBoth essential oils exhibited inhibitory effects toward all test organisms, indicated by inhibition zones around the disk. The MIC values of clove essential oil were 0.078% (v/v) for all tested bacteria, whereas the MICs of cinnamon essential oil ranged from 0.039% (v/v) to 0.156% (v/v) for all tested bacteria. MBC values of clove and cinnamon essential oils ranged from 0.078% (v/v) to 0.156% (v/v) for all tested bacteria. There were morphological changes in each tested bacterial cell that was observed through SEM. Each tested bacteria treated with clove and cinnamon essential oils showed shrinkage and cells lysis.

conclusionIt was concluded that clove and cinnamon essential oils have emerged as effective antibacterial agents by showing high antibacterial activity against ESBL-producing

Indexed as

cinnamon (Cinnamomum burmannii)clove (Syzygium aromaticum)Escherichia coliessential oilsextended-spectrum β-lactamaseKlebsiella pneumoniae

Identifiers

PMID34566340
PMCPMC8448639
OpenAlexW3195933739

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.