Evidence map›Paper›PMID 34565525›Full record

ArticleThe Journal of arthroplasty2021

Adjusted Survival Curves Improve Understanding of Multivariable Cox Model Results.

Carly S Lundgreen, Dirk R Larson, Elizabeth J Atkinson, Katrina L Devick, David G Lewallen, Daniel J Berry, Hilal Maradit Kremers, Cynthia S Crowson

Abstract read
In one paragraph

Article in The Journal of arthroplasty, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Compliant sports floors and fall-related injuries: evidence from a residential care setting and updated meta-analysis for all patient care settings.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2023
    Pooled it
  2. Article
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  8. Observational
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  14. Living With Survival Analysis in Orthopedics.The Journal of arthroplasty · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carly S LundgreenDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Dirk R LarsonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Elizabeth J AtkinsonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Katrina L DevickDepartment of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ.
David G LewallenDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Daniel J BerryDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Hilal Maradit KremersDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Cynthia S CrowsonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Division of Rheumatology, Mayo Clinic, Rochester, MN.

Funding

Resource CoreP30AR076312 · NIAMS · MAYO CLINIC ROCHESTER · PI Daniel Berry · 2019 to 2026
$5.5M
NIAMS NIH HHS P30 AR076312
6 · The paper itself

Abstract

Kaplan-Meier survival curves are the most common methods for unadjusted group comparison of outcomes in orthopedic research. However, they may be misleading due to an imbalance of confounders between patient groups. The Cox model is frequently used to adjust for confounders, but graphical display of adjusted survival curves is not commonly utilized. We describe the circumstances when adjusted survival curves are useful in orthopedic research, describe and use 2 different methods to obtain adjusted curves, and illustrate how they can improve understanding of the multivariable Cox model results. We further provide practical strategies for identifying the need for and performing adjusted survival curves. Please visit the followinghttps://youtu.be/ys0hy2CiMCAfor a video that explains the highlights of the paper in practical terms.

Indexed as

Proportional Hazards ModelsHumansKaplan-Meier EstimateSurvival AnalysisconfoundingCox modelsurvival analysissurvival curvestotal joint arthroplasty

Identifiers

PMID34565525
PMCPMC8476943

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.