ArticleOrphanet journal of rare diseases2021
Clinical features of lupus enteritis: a single-center retrospective study.
Article in Orphanet journal of rare diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Autoimmune diseases involving the gastrointestinal tract: clinical patterns, imaging spectrum, and complications.Abdominal radiology (New York) · 2026Review
- Article
- Analysis of clinical features of lupus mesenteric vasculitis.Clinical and experimental medicine · 2026Article
- Ischemic duodenal injury due to systemic lupus erythematosus: A case report.World journal of gastroenterology · 2026Article
- Establishment of a novel lupus mesenteric vasculitis mouse model and exploration of its exacerbation mechanisms.Frontiers in immunology · 2026Article
- Lupus Enteritis Presenting as Acute Abdomen with Clear Gelatinous Stools in a Woman with Systemic Lupus Erythematosus: A Case Report and Literature Review.Open access rheumatology : research and reviews · 2026Article
- Article
- Low-dose rituximab in lupus enteritis: a comparative study on its efficacy in modulating mucosal immunity and reducing inflammation.Arthritis research & therapy · 2025Article
- An Observational Study on Clinical Insights and Outcome Prediction of Lupus Enteritis in Indian Systemic Lupus Erythematosus Patients.Mediterranean journal of rheumatology · 2025Article
- Severe Lupus Enteritis in a Regional Hospital: An Uncommon Presentation of the Acute Surgical Abdomen.Case reports in surgery · 2025Article
- Clinical features, imaging findings, and outcomes of acute abdominal pain in systemic lupus erythematosus: comparing mesenteric vasculitis, non-mesenteric vasculitis, and surgical conditions.Clinical rheumatology · 2024Article
- Lupus enteritis as systemic lupus erythematosus main manifestation: Two case reports.SAGE open medical case reports · 2024Article
- Rare case of lupus enteritis presenting as colorectum involvement: A case report and review of literature.World journal of clinical cases · 2023Article
- Severe Lupus Enteritis Complicated by Intractable Gastrointestinal Hemorrhage.ACG case reports journal · 2023Article
- Acute flare of systemic lupus erythematosus with extensive gastrointestinal involvement: A case report and review of literature.World journal of gastrointestinal surgery · 2023Article
- Complement as a Biomarker for Systemic Lupus Erythematosus.Biomolecules · 2023Review
- Autoimmune Lupus Enteritis with Pan Gastrointestinal Involvement in an Adult Patient with Systemic Lupus Erythematosus: Complete Response to Belimumab.Journal of community hospital internal medicine perspectives · 2023Article
- Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLupus enteritis (LEn) is a rare complication of systemic lupus erythematosus (SLE). Timely diagnosis and treatment of LEn are necessary to prevent the most serious consequences - intestinal perforation, gastrointestinal bleeding, and death. We compared the clinical features of SLE patients with and without LEn.
methodsThe clinical data of LEn inpatients at Suining Central Hospital from July 2012 to June 2020 were examined. These LEn patients were matched (1:2 ratio) with concurrently hospitalized SLE patients who did not have LEn. The two groups were compared using multivariate logistic regression.
resultsWe compared SLE inpatients with LEn (n = 43) and SLE inpatients without LEn (n = 86) at our institution. Multivariate logistic regression showed that ascites (odds ratio [OR]: 9.961, 95%CI: 2.215-44.802, P = 0.003), hydronephrosis (OR: 28.060, 95%CI: 2.303-341.962, P = 0.009), leukopenia (OR: 5.890, 95%CI: 1.813-19.135, P = 0.003), reduced complement C3 level (OR: 4.791, 95%CI: 1.605-14.300, P = 0.005), and elevated immunoglobin (Ig)A level (OR: 4.040, 95%CI: 1.307-12.487, P = 0.015) were independently associated with LEn. Within the LEn group, abdominal pain was the most common abdominal symptom (88.4%), and increased mesenteric fat attenuation (74.4%) and bowel wall thickening (58.1%) were the most common computed tomography (CT) findings. Most LEn patients (88.4%) required high-dose glucocorticoid therapy (≥ 80 mg methylprednisolone/day), and cyclophosphamide was the most commonly used immunosuppressant (62.8%).
conclusionsAbdominal pain was the most common clinical symptom of LEn. Abdominal CT provides important information for detection and diagnosis of LEn. Ascites, hydronephrosis, leukopenia, hypocomplementemia (C3), and increased IgA were independently associated with LEn.
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