Evidence map›Paper›PMID 34565312›Full record

ReviewBiochemistry. Biokhimiia2021

Non-Canonical Translation Initiation Mechanisms Employed by Eukaryotic Viral mRNAs.

Ivan I Sorokin, Konstantin S Vassilenko, Ilya M Terenin, Natalia O Kalinina, Vadim I Agol, Sergey E Dmitriev

Open access · bronzeAbstract readReview
In one paragraph

Review in Biochemistry. Biokhimiia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 56 citations in OpenAlex.

  1. Viral RNAs as Dual Graphs: Extending the Motif Universe of RNAs.bioRxiv : the preprint server for biology · 2026
    Article
  2. Enhancement of Therapeutic mRNA Translation in Cellular Stress Conditions.International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ivan I SorokinBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Konstantin S VassilenkoInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Ilya M TereninBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Natalia O KalininaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Vadim I AgolBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Sergey E DmitrievBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. sergey.dmitriev@belozersky.msu.ru.
Institute of Protein Research · RULomonosov Moscow State University · RUEngelhardt Institute of Molecular Biology · RUInstitute of Bioorganic Chemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses exploit the translation machinery of an infected cell to synthesize their proteins. Therefore, viral mRNAs have to compete for ribosomes and translation factors with cellular mRNAs. To succeed, eukaryotic viruses adopt multiple strategies. One is to circumvent the need for m

Indexed as

AnimalsEukaryotic CellsHumansInternal Ribosome Entry SitesPeptide Chain Initiation, TranslationalRNA, CircularRNA, MessengerRNA, ViralViral ProteinsInternal Ribosome Entry SitesRNA, CircularRNA, MessengerRNA, ViralViral Proteinscap-independent translationcircular RNAscoronavirus SARS-CoV-2flaviviruses HCV and DENVIRES and 3′ CITElentiviruses HIV-1 and HIV-2picornaviruses PV and EMCVtranslation initiation factors eIF2 and eIF4FTURBS-mediated reinitiationVPg

Identifiers

PMID34565312
PMCPMC8436584
OpenAlexW3199749282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.