Evidence map›Paper›PMID 34565194›Full record

ArticleInternational journal of immunopathology and pharmacology

A multicenter survey on the aspects of everyday life in adult patients with primary antibody deficiencies treated with immunoglobulin G replacement during the COVID-19 pandemic.

Katarzyna Napiórkowska-Baran, Tomasz Rosada, Ewa Więsik-Szewczyk, Marcin Ziętkiewicz, Aleksandra Matyja-Bednarczyk, Karolina Baranowska, Ewa Alska, Marta Tykwińska, Ewa Szynkiewicz, Robert Zacniewski and 2 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Katarzyna Napiórkowska-BaranDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.ORCID https://orcid.org/0000-0003-2202-3222
Tomasz RosadaDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Ewa Więsik-SzewczykDepartment of Internal Medicine, Pulmonology, Allergy and Clinical Immunology, 49586Military Institute of Medicine in Warsaw, Warsaw, Poland.ORCID https://orcid.org/0000-0001-8509-4453
Marcin ZiętkiewiczDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, 37804Medical University of Gdansk, Gdansk, Poland.ORCID https://orcid.org/0000-0002-0186-4009
Aleksandra Matyja-Bednarczyk2nd Department of Internal Medicine, 37799Jagiellonian University Medical College, Krakow, Poland.
Karolina BaranowskaDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Ewa AlskaDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Marta TykwińskaDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Ewa SzynkiewiczDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Robert ZacniewskiDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Kinga GrochowalskaDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, 37804Medical University of Gdansk, Gdansk, Poland.
Zbigniew BartuziDepartment and Clinic of Allergology, Clinical Immunology and Internal Diseases, 49604Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Nicolaus Copernicus University · PLGdańsk Medical University · PLJagiellonian University · PLWojskowy Instytut Medycyny Lotniczej · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 pandemic has changed many aspects of everyday life. Patients with primary immunodeficiency (PID) are in a particularly difficult situation. The purpose of the present study was to contribute to the very limited research on the everyday aspects of functioning in PID patients during the COVID-19 pandemic.

methodsThe survey included 85 adult PID patients treated with immunoglobulin replacement therapy in four reference centers for immunology. Everyday functioning of the patients as well as their opinion concerning new solutions in medical care were analyzed.

resultsDuring the pandemic, the percentage of patients experiencing fear/anxiety has increased from 47% to 70%. The wide dissemination of information about the SARS-CoV-2 in the media has increased anxiety in 40% of the patients. Patients diagnosed with PID were most afraid of the exposure to contact with strangers, especially in public places. As many as 67 respondents (79%) considered the introduction of restrictions concerning social functioning as good. Only every fifth person learned about the pandemic from reliable sources. Eighty three percent of the patients receiving immunoglobulin substitution experienced less fear of SARS-CoV-2 infection. The patients positively evaluated the solutions related to the direct delivery of drugs to the place of residence in order to continue home IgRT therapy. Fifty three respondents (62.5%) believed that the possibility of a remote consultation was a very good solution.

conclusionIt is necessary to increase educational activities concerning the pandemic provided by health care professionals, as patients obtain information mainly from the media and the Internet, which adversely affects the feeling of anxiety. The pandemic, in addition to the very negative impact on patients and the deterioration of their daily functioning, has made patients appreciate their life more, devote more time to family and friends, and do things they like.

Indexed as

Activities of Daily LivingCOVID-19Immunocompromised HostAccess to InformationAdultAffectAnxietyCost of IllnessDrug SubstitutionFearFemaleHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansImmunoglobulin GMaleImmunoglobulin GadultanxietyCOVID-19fearimmunoglobulin treatmentmedical careprimary antibody deficiencyprimary immunodeficienciesquality of lifeSARS-CoV-2

Identifiers

PMID34565194
PMCPMC8481708
OpenAlexW3202248799

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.