Evidence map›Paper›PMID 34565170›Full record

ArticleJCO oncology practice2022

Trainee-Led Quality Improvement Project to Improve Fertility Preservation Counseling for Patients With Cancer.

Laura A Sena, Ramy Sedhom, Susan Scott, Amanda Kagan, Andrew H Marple, Jenna V Canzoniero, Melinda Hsu, Syed M Qasim Hussaini, Amin S Herati, Lauren Reschke and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Counseling and use of surrogacy among cancer survivors (CUSACS).Journal of cancer survivorship : research and practice · 2026
    Article
  2. Article
  3. Article
  4. Perceived impact of a decision-aid and planning tool for family building after cancer for young adult female cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Laura A SenaThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Ramy SedhomThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0001-8937-0726
Susan ScottThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0002-1797-1685
Amanda KaganThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0002-1953-2029
Andrew H MarpleThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Jenna V CanzonieroThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0003-1084-6918
Melinda HsuThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0003-0200-1579
Syed M Qasim HussainiThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0002-8006-5343
Amin S HeratiDepartment of Urology, Johns Hopkins University, Baltimore, MD.
Lauren ReschkeDepartment of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MD.
Maria Facadio AnteroDepartment of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MD.
Mindy S ChristiansonDepartment of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MD.
Adam F BinderDepartment of Oncology, Thomas Jefferson University, Philadelphia, PA.ORCID 0000-0001-8101-6335
Allen R ChenThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Ross C DonehowerThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Kristen A MarroneThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Arjun GuptaThe Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.ORCID 0000-0003-0875-4731
Johns Hopkins University · USThomas Jefferson University · USUniversity of Minnesota · US

Funding

ONCOLOGY: CHEMOTHERAPY, IMMUNOLOGY, BIOLOGYT32CA009071 · NCI · JOHNS HOPKINS UNIVERSITY · PI Mary Y Armanios, Nilofer S. Azad · 1985 to 2026
$12.8M
Clinical Pharmacology Training ProgramT32GM066691 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Matthew Michael Ippolito · 2003 to 2026
$6.4M
NCI NIH HHS T32 CA009071NIGMS NIH HHS T32 GM066691
6 · The paper itself

Abstract

purposeOncofertility counseling regarding the reproductive risks associated with cancer therapy is essential for quality cancer care. We aimed to increase the rate of oncofertility counseling for patients of reproductive age (18-40 years) with cancer who were initiating systemic therapy at the Johns Hopkins Cancer Center from a baseline rate of 37% (25 of 68, June 2019-January 2020) to 70% by February 2021.

methodsWe formed an interprofessional, multidisciplinary team as part of the ASCO Quality Training Program. We obtained data from the electronic medical record and verified data with patients by phone. We surveyed patients, oncologists, and fertility specialists to identify barriers. After considering a prioritization matrix, we implemented Plan-Do-Study-Act (PDSA) cycles.

resultsWe identified the following improvement opportunities: (1) oncologist self-reported lack of knowledge about counseling and local fertility preservation options and (2) lack of a standardized referral mechanism to fertility services. During the first PDSA cycle (February 2020-August 2020, disrupted by COVID-19), we introduced the initiative to increase oncofertility counseling at faculty meetings. From September 2020 to November 2020, we implemented a second PDSA cycle: (1) educating and presenting the initiative at Oncology Grand Rounds, (2) distributing informative pamphlets to oncologists and patients, and (3) implementing an electronic medical record order set. In the third PDSA cycle (December 2020-February 2021), we redesigned the order set to add information (eg, contact information for fertility coordinator) to the patient after-visit summary. Postimplementation (September 2020-February 2021), counseling rates increased from 37% to 81% (38 of 47).

conclusionWe demonstrate how a trainee-led, patient-centered initiative improved oncofertility care. Ongoing work focuses on ensuring sustainability and assessing the quality of counseling.

Indexed as

COVID-19Fertility PreservationNeoplasmsAdolescentAdultCounselingHumansQuality ImprovementSARS-CoV-2Young Adult

Identifiers

PMID34565170
PMCPMC8932487
OpenAlexW3202776674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.