ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2021
Ecofriendly preparation of silver nanoparticles-based nanocomposite stabilized by polysaccharides with antibacterial, antifungal and antiviral activities.
Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Development of poly-D-mannose-stabilized silver nanoparticles exhibiting antibacterial and antibiofilm properties.Applied and environmental microbiology · 2025Article
- A novel clotrimazole selenium nano-composite for combating deep dermal Candida albicans infections and virulence genes.The Journal of antibiotics · 2025Article
- Low-Frequency Ultrasound Assisted in Improvement in Cell Development and Production of Parasporal Crystals fromInsects · 2025Article
- Silver Nanoparticle-Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review.Global challenges (Hoboken, NJ) · 2025Review
- Recent advances of silver nanoparticle-based polymer nanocomposites for biomedical applications.RSC advances · 2025Review
- Review
- Nanotechnology in cancer treatment: revolutionizing strategies against drug resistance.Frontiers in bioengineering and biotechnology · 2025Review
- Silver nanoparticles as next-generation antimicrobial agents: mechanisms, challenges, and innovations against multidrug-resistant bacteria.Frontiers in cellular and infection microbiology · 2025Review
- Sustainable Primary Cell Banking for Topical Compound Cytotoxicity Assays: Protocol Validation on Novel Biocides and Antifungals for Optimized Burn Wound Care.European burn journal · 2024Article
- Comprehensive antifungal investigation of green synthesized silver nanoformulation against four agriculturally significant fungi and its cytotoxic applications.Scientific reports · 2024Article
- Biosynthesis of Bt-AgApplied microbiology and biotechnology · 2024Article
- Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Lawsonia inermis Against Common Pathogens from Urinary Tract Infection.Applied biochemistry and biotechnology · 2024Article
- Advances in silver nanoparticles: a comprehensive review on their potential as antimicrobial agents and their mechanisms of action elucidated by proteomics.Frontiers in microbiology · 2024Review
- Antiviral polysaccharide and antiviral peptide delivering nanomaterials for prevention and treatment of SARS-CoV-2 caused COVID-19 and other viral diseases.Journal of controlled release : official journal of the Controlled Release Society · 2023Review
- Antibacterial activity of CuO-Ag Janus like nanoparticles against recombinant strain Escherichia coli.Archives of microbiology · 2023Article
- Acrylonitrile adducts: design, synthesis and biological evaluation as antimicrobial, haemolytic and thrombolytic agent.Scientific reports · 2023Article
- Cytotoxic and Bactericidal Effects of Inhalable Ciprofloxacin-Loaded Poly(2-ethyl-2-oxazoline) Nanoparticles with Traces of Zinc Oxide.International journal of molecular sciences · 2023Article
- Biosynthesis of Silver and Gold Nanoparticles and Their Efficacy Towards Antibacterial, Antibiofilm, Cytotoxicity, and Antioxidant Activities.Applied biochemistry and biotechnology · 2023Article
- Nanoparticles: Taking a Unique Position in Medicine.Nanomaterials (Basel, Switzerland) · 2023Review
- Potential Antimicrobial and Antibiofilm Properties of Copper Oxide Nanoparticles: Time-Kill Kinetic Essay and Ultrastructure of Pathogenic Bacterial Cells.Applied biochemistry and biotechnology · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present work, sustainable and green method was used to prepare silver nanoparticles (Ag-NPs), followed with incorporation into tertiary nanocomposite consisted of starch, oxidized cellulose and ethyl cellulose. The prepared tertiary silver-nanocomposite (Ag-NC) was fully characterized via instrumental analysis (UV-vis, FT-IR, XRD, SEM, EDX and TEM) and evaluated for antibacterial, antifungal, and antiviral activities. Ag-NC significantly suppressed growth of tested bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis) as compared with controls. Antifungal activity revealed that the prepared tertiary Ag-NC has a promising antifungal activity towards unicellular (Candida albicans) and multicellular fungi ( Aspergillus niger, A. terreus, A. flavus and A. fumigatus). In same line, both Ag-NC and free Ag-NPs have shown a dose-dependent reduction in Vero cell line with maximum non-toxic dose at 6.25 and 12.5 μg/mL, respectively. Both Ag-NPs and Ag-NC exhibited antiviral effects against Herpes simplex virus, Adenovirus and Coxsackie B virus in a dose-dependent manner. Combined treatment of Ag-NPs incorporated into tertiary nanocomposite based on starch, oxidized cellulose and ethyl cellulose opens new possibilities to be more efficient nanomaterials for preventing microbial growth. In conclusion, the prepared tertiary Ag-NC has a promising antibacterial, antifungal as well as antiviral activities.
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