Evidence map›Paper›PMID 34564797›Full record

ArticleDermatology and therapy2021

Electrocardiogram Findings in Patients with Alopecia Areata.

Danielle Peterson, Carlos Wambier, Feng Dai, Rachel Lampert, Tariq Ahmad, Katerina L Yale, Natasha A Mesinkovska, Brett King

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Danielle Peterson *Department of Dermatology, Yale School of Medicine, New Haven, CT, USA.
Carlos Wambier *Department of Dermatology, Brown University, Providence, RI, USA.
Feng DaiCenter for Analytical Sciences, Yale School of Medicine, New Haven, CT, USA.
Rachel LampertDepartment of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
Tariq AhmadDepartment of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA. tariq.ahmed@yale.edu.
Katerina L YaleDepartment of Dermatology, University of California, Irvine, Irvine, CA, USA.
Natasha A MesinkovskaDepartment of Dermatology, University of California, Irvine, Irvine, CA, USA.
Brett KingDepartment of Dermatology, Yale School of Medicine, New Haven, CT, USA. brett.king@yale.edu.ORCID http://orcid.org/0000-0002-4576-4616
Yale University · USUniversity of California, Irvine · USBrown University · USYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

introductionWhile autoimmune comorbidities are common in alopecia areata, little is known about comorbid cardiovascular disease. The purpose of this study was to evaluate the incidence of bradyarrhythmia in patients with alopecia areata.

methodsRetrospective review of electrocardiograms of 124 patients with [Formula: see text] 50% scalp hair loss (severe alopecia areata) was conducted and compared to National Health and Nutrition Examination Survey (NHANES) data.

resultsThe prevalence of bradycardia in females with alopecia areata was 24.3% (95% CI, 14.5-34.1%) and in those age 40 years or older was 40.8% (95% CI, 22.2-53.5%) compared to 19.5% in the NHANES III population. The prevalence of bradycardia in males with alopecia areata was 36.0% (95% CI, 22.7-49.3%) and in those age 40 years or older was 50.0% (95% CI, 21.7-78.3%) compared to 26.9% in the NHANES III population.

conclusionThe potential association between bradycardia and alopecia areata merits further investigation.

Indexed as

Alopecia areataAutoimmuneBradycardiaCardiovascularElectrocardiogramHeart rateT cell

Identifiers

PMID34564797
PMCPMC8611143
OpenAlexW3203364865

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.