Evidence map›Paper›PMID 34564777›Full record

ArticleAIDS and behavior2022

Multilevel Analysis of Individual and Neighborhood Characteristics Associated with Viral Suppression Among Adults with HIV in Rio de Janeiro, Brazil.

Lyolya Hovhannisyan, Lara E Coelho, Luciane Velasque, Raquel B De Boni, Jesse Clark, Sandra W Cardoso, Jordan Lake, Valdilea G Veloso, Beatriz Grinsztejn, Paula M Luz

Erratum issuedAbstract read
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Lyolya HovhannisyanSouth American Program in HIV Prevention Research (SAPHIR), University of California Los Angeles, Los Angeles, USA. Lyolya.hovhannisyan@gmail.com.ORCID http://orcid.org/0000-0001-6472-9165
Lara E CoelhoInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Luciane VelasqueUniversidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, Brazil.
Raquel B De BoniInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Jesse ClarkSouth American Program in HIV Prevention Research (SAPHIR), University of California Los Angeles, Los Angeles, USA.
Sandra W CardosoInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Jordan LakeSouth American Program in HIV Prevention Research (SAPHIR), University of California Los Angeles, Los Angeles, USA.
Valdilea G VelosoInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Beatriz GrinsztejnInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Paula M LuzInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
CCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M
South American Program in HIV Prevention Research (SAPHIR)R25MH087222 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Karin Nielsen · 2011 to 2026
$3.9M
QUANTITATIVE STUDIES OF THE CENTRAL VISUAL SYSTEMR01EY002017 · NEI · NEW YORK UNIVERSITY · PI MOVSHON, J ANTHONY · 1986 to 2008
$1.7M
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/203.154/2017Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR) 310541/2017-4Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR) E-26/203.287/2016Instituto Nacional de Ciência e Tecnologia 306196/2017-4Instituto Nacional de Ciência e Tecnologia 310541/2017-4National Institute of Allergy and Infectious Diseases U01AI069923NIAID NIH HHS U01 AI069923NIMH NIH HHS MH087222NIMH NIH HHS P30 MH058107NIMH NIH HHS R25 MH087222
6 · The paper itself

Abstract

Understanding the impact of neighborhood context on viral suppression outcomes may help explain health disparities and identify future interventions. We assessed the relationship between individual characteristics, neighborhood socioeconomic context, and viral suppression using multilevel logistic regression models. Adults with HIV initiating antiretroviral therapy (ART) between 2000 and 2017, who resided in Rio de Janeiro and had an HIV-1 RNA level (viral load) measured 90-270 days after ART initiation were included. Overall, 83.9% achieved viral suppression. Participants who were older, had a higher level of education, and identified as heterosexual cisgender men and cisgender men-who-have-sex-with-men had increased odds of viral suppression. Later calendar year of ART initiation carried the strongest association with viral suppression, reflecting the increased effectiveness and tolerability of ART over time. Neighborhood socioeconomic indicators did not predict viral suppression in unadjusted or adjusted analyses, which may result from the integrated care provided in our health care facility together with Brazil's universal treatment.

Indexed as

HIV InfectionsSexual and Gender MinoritiesAdultBrazilHomosexuality, MaleHumansMaleMultilevel AnalysisNeighborhood CharacteristicsViral LoadARTBrazilHIV/AIDSLMICNeighborhood characteristicsViral suppression

Identifiers

PMID34564777
PMCPMC8898026

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.