ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2022
The mismatch negativity responses of individuals with tinnitus with normal extended high-frequency hearing-is it possible to use mismatch negativity in the evaluation of tinnitus?
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Investigation of the effectiveness of sound enrichment in the treatment of tinnitus due to hearing loss.Brain and behavior · 2024Trial
- Central Abnormalities in Idiopathic Tinnitus With Mild Hearing Loss: Selective Attention and Preprocessing Dysfunction.Brain and behavior · 2026Article
- Prolonged P3 latency predicts clinical response to repetitive transcranial magnetic stimulation in tinnitus.Clinical neurophysiology practice · 2026Article
- Abnormally enhanced temporal correlations of alpha oscillations across multiple timescales in tinnitus patients.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- What Do Mismatch Negativity (MMN) Responses Tell Us About Tinnitus?Journal of the Association for Research in Otolaryngology : JARO · 2025Review
- Repetition positivity following auditory intensity or frequency changes in young normal-hearing adults.Frontiers in neuroscience · 2025Article
- Investigation of the behavior of tinnitus patients under varying listening conditions with simultaneous electroencephalography and pupillometry.Brain and behavior · 2024Article
- Investigating sensitivity to multi-domain prediction errors in chronic auditory phantom perception.Scientific reports · 2024Article
- Development, Insults and Predisposing Factors of the Brain's Predictive Coding System to Chronic Perceptual Disorders-A Life-Course Examination.Brain sciences · 2024Article
- Objective Detection of Tinnitus Based on Electrophysiology.Brain sciences · 2022Review
- Application of auditory mismatch negativity in tinnitus patients based on high-resolution electroencephalogram signals.Translational neuroscience · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study uses the multi-feature paradigm to compare the MMN responses of individuals with normal hearing thresholds, including the high frequencies with and without tinnitus.
methodsSixteen subjects with chronic subjective idiopathic tinnitus and twenty matched healthy controls were included in the study. Participants with hearing thresholds (0.125-16 kHz) less than 20 dB HL and MoCA test scores above 21 were included in the study. MMN responses and topographical maps of the responses resulting from the multi-feature MMN paradigm were recorded from 22 surface scalp electrodes. Amplitude and latency parameters of the MMN responses of five different deviants, consisting of frequency, intensity, duration, location, and silent gap, were compared between the two groups.
resultsThe amplitudes of MMN responses were lower in the tinnitus group than in the control group at Fz electrode for all deviant types. At the same time, there was no difference between the groups for MMN latencies and, no correlation was found between THI and MMN.
conclusionAccording to our results, the MMN might indicate a possible impairment in pre-attentive and automatic central auditory processing for chronic tinnitus patients. Since MMN responses in the tinnitus group differ from those of healthy individuals, it might be used as a reference for evaluating the central auditory pathways of tinnitus patients.
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