ArticleEuropean radiology2022
Precision of MRI radiomics features in the liver and hepatocellular carcinoma.
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 40 citations in OpenAlex.
- Assessment of Robustness of MRI Radiomic Features in Four Abdominal Organs: Impact of Deep Learning Reconstruction and Segmentation.Journal of magnetic resonance imaging : JMRI · 2026Article
- Assessment of Robustness of MRI Radiomic Features in the Abdomen: Impact of Deep Learning Reconstruction and Accelerated Acquisition.Journal of imaging informatics in medicine · 2026Article
- Reproducibility of MRI Radiomics Measurements in Men with Prostate Cancer Undergoing Active Surveillance.Cancers · 2026Article
- [Effect of AI-assisted compressed sensing acceleration on MRI radiomic feature extraction and staging model performance for nasopharyngeal carcinoma].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Development and Validation of a Modality-Invariant 3D Swin U-Net Transformer for Liver and Spleen Segmentation on Multi-Site Clinical Bi-parametric MR Images.Journal of imaging informatics in medicine · 2025Article
- Prediction of contralateral central lymph node metastasis in unilateral papillary thyroid carcinoma based on radiomics.Scientific reports · 2025Article
- Alpha-fetoprotein combined with initial tumor shape irregularity in predicting the survival of patients with advanced hepatocellular carcinoma treated with immune-checkpoint inhibitors: a retrospective multi-center cohort study.Journal of gastroenterology · 2025Article
- Investigation of ComBat Harmonization on Radiomic and Deep Features from Multi-Center Abdominal MRI Data.Journal of imaging informatics in medicine · 2025Article
- Harnessing big data for precision medicine: radiomics based application of nanomaterials in MRI enhancement and multimodal therapy of hepatocellular carcinoma.Frontiers in immunology · 2025Review
- Characterization of renal masses with MRI-based radiomics: assessment of inter-package and inter-observer reproducibility in a prospective pilot study.Abdominal radiology (New York) · 2024Article
- Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer.Physics and imaging in radiation oncology · 2024Article
- Enhancing the Clinical Utility of Radiomics: Addressing the Challenges of Repeatability and Reproducibility in CT and MRI.Diagnostics (Basel, Switzerland) · 2024Review
- Reproducibility Analysis of Radiomic Features on T2-weighted MR Images after Processing and Segmentation Alterations in Neuroblastoma Tumors.Radiology. Artificial intelligence · 2024Article
- Establishment and validation of a nomogram containing cytokeratin fragment antigen 21-1 for the differential diagnosis of intrahepatic cholangiocarcinoma and hepatocellular carcinoma.Frontiers in oncology · 2024Article
- Article
- Investigating the Feasibility of Predicting KRAS Status, Tumor Staging, and Extramural Venous Invasion in Colorectal Cancer Using Inter-Platform Magnetic Resonance Imaging Radiomic Features.Diagnostics (Basel, Switzerland) · 2023Article
- Reproducibility and location-stability of radiomic features derived from cone-beam computed tomography: a phantom study.Dento maxillo facial radiology · 2023Article
- Focal Lesions of the Liver and Radiomics: What Do We Know?Diagnostics (Basel, Switzerland) · 2023Review
- Advances in application of novel magnetic resonance imaging technologies in liver disease diagnosis.World journal of gastroenterology · 2023Review
- Deep learning nomogram based on Gd-EOB-DTPA MRI for predicting early recurrence in hepatocellular carcinoma after hepatectomy.European radiology · 2023Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
Abstract
objectivesTo assess the precision of MRI radiomics features in hepatocellular carcinoma (HCC) tumors and liver parenchyma.
methodsThe study population consisted of 55 patients, including 16 with untreated HCCs, who underwent two repeat contrast-enhanced abdominal MRI exams within 1 month to evaluate: (1) test-retest repeatability using the same MRI system (n = 28, 10 HCCs); (2) inter-platform reproducibility between different MRI systems (n = 27, 6 HCCs); (3) inter-observer reproducibility (n = 16, 16 HCCs). Shape and 1st- and 2nd-order radiomics features were quantified on pre-contrast T1-weighted imaging (WI), T1WI portal venous phase (pvp), T2WI, and ADC (apparent diffusion coefficient), on liver regions of interest (ROIs) and HCC volumes of interest (VOIs). Precision was assessed by calculating intraclass correlation coefficient (ICC), concordance correlation coefficient (CCC), and coefficient of variation (CV).
resultsThere was moderate to excellent test-retest repeatability of shape and 1st- and 2nd-order features for all sequences in HCCs (ICC: 0.53-0.99; CV: 3-29%), and moderate to good test-retest repeatability of 1st- and 2nd-order features for T1WI sequences, and 2nd-order features for T2WI in the liver (ICC: 0.53-0.73; CV: 12-19%). There was poor inter-platform reproducibility for all features and sequences, except for shape and 1st-order features on T1WI in HCCs (CCC: 0.58-0.99; CV: 3-15%). Good to excellent inter-observer reproducibility was found for all features and sequences in HCCs (CCC: 0.80-0.99; CV: 4-15%) and moderate to good for liver (CCC: 0.45-0.86; CV: 6-25%).
conclusionsMRI radiomics features have acceptable repeatability in the liver and HCC when using the same MRI system and across readers but have low reproducibility across MR systems, except for shape and 1st-order features on T1WI. Data must be interpreted with caution when performing multiplatform radiomics studies. KEY POINTS: • MRI radiomics features have acceptable repeatability when using the same MRI system but less reproducible when using different MRI platforms. • MRI radiomics features extracted from T1 weighted-imaging show greater stability across exams than T2 weighted-imaging and ADC. • Inter-observer reproducibility of MRI radiomics features was found to be good in HCC tumors and acceptable in liver parenchyma.
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