Evidence map›Paper›PMID 34564737›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2022

Osteoarthritic and non-osteoarthritic patients show comparable coronal knee joint line orientations in a cross-sectional study based on 3D reconstructed CT images.

Silvan Hess, Lukas B Moser, Emma L Robertson, Henrik Behrend, Felix Amsler, Edna Iordache, Vincent Leclercq, Michael T Hirschmann

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

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0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Trial
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  3. Personalized alignment in total knee arthroplasty reduces patellar tilt: A retrospective study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
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  7. Increased prevalence and severity of femoral bone wear in Japanese patients with varus knee osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Inverse kinematic total knee arthroplasty using conventional instrumentation restores constitutional coronal alignment.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2024
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Silvan HessDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland.
Lukas B MoserDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland.
Emma L RobertsonDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland.
Henrik BehrendDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Felix AmslerAmsler Consulting, Basel, Switzerland.
Edna IordacheDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland.
Vincent LeclercqSymbios, Yverdon les Bains, Switzerland.
Michael T HirschmannDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland. michael.hirschmann@unibas.ch.ORCID http://orcid.org/0000-0002-4014-424X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecently introduced total knee arthroplasty (TKA) alignment strategies aim to restore the pre-arthritic alignment of an individual patient. The native alignment of a patient can only be restored with detailed knowledge about the native and osteoarthritic alignment as well as differences between them. The first aim of this study was to assess the alignment of a large series of osteoarthritic (OA) knees and investigate whether femoral and tibial joint lines vary within patients with the same overall lower limb alignment. The secondary aim was to compare the alignment of OA patients to the previously published data of non-OA patients. This information could be useful for surgeons considering implementing one of the new alignment concepts. MATERIAL: Coronal alignment parameters of 2692 knee OA patients were measured based on 3D reconstructed CT data using a validated planning software (Knee-PLAN

resultsFemoral and tibial joint lines varied within patients with the same overall lower limb alignment. A total of 162 functional knee phenotypes were found (119 males, 136 females and 94 mutual phenotypes). Mean values differed between the OA and non-OA population, but differences were small (< 2°) except for the overall alignment (e.g. HKA). The distribution of OA and non-OA patients among the phenotypes differed significantly, especially among the limb phenotypes.

conclusionDifferences between OA and non-OA knees are small regarding coronal femoral and tibial joint line orientation. Femoral and tibial joint line orientation of osteoarthritic patients can, therefore, be used to estimate their native coronal alignment and plan an individualized knee alignment. LEVEL OF CLINICAL EVIDENCE: III.

Indexed as

Osteoarthritis, KneeTibiaCross-Sectional StudiesFemaleFemurHumansKnee JointLower ExtremityMaleTomography, X-Ray ComputedCoronal alignmentDistal femoral angleHip-knee-ankle angleKneeOsteoarthritisPhenotypesProximal tibial angleTotal knee arthroplasty

Identifiers

PMID34564737
PMCPMC8866364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.