Evidence map›Paper›PMID 34564574›Full record

ArticleVeterinary sciences2021

Comparative Analysis of

Eunice Magoma Machuka, Anne W Thairu Muigai, Joshua Oluoch Amimo, Jean-Baka Domelevo Entfellner, Isaac Lekolool, Edward Okoth Abworo, Roger Pelle

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Eunice Magoma MachukaBiosciences Eastern and Central Africa, International Livestock Research Institute (BecA-ILRI) Hub, Nairobi P.O. Box 30709-00100, Kenya.ORCID 0000-0002-1142-3442
Anne W Thairu MuigaiBotany Department, Jomo Kenyatta University of Agriculture and Technology, Nairobi P.O. Box 62000-00200, Kenya.ORCID 0000-0001-5164-8921
Joshua Oluoch AmimoCenter for Food Animal Health, Department of Animal Sciences, 1680 Madison Avenue, The Ohio State University, Wooster, OH 44691, USA.ORCID 0000-0002-4190-8483
Jean-Baka Domelevo EntfellnerBiosciences Eastern and Central Africa, International Livestock Research Institute (BecA-ILRI) Hub, Nairobi P.O. Box 30709-00100, Kenya.ORCID 0000-0002-8282-1325
Isaac LekoloolKenya Wildlife Services, Nairobi P.O. Box 40241-00100, Kenya.
Edward Okoth AbworoAnimal and Human Health Program, International Livestock Research Institute, Nairobi P.O. Box 30709-00100, Kenya.
Roger PelleBiosciences Eastern and Central Africa, International Livestock Research Institute (BecA-ILRI) Hub, Nairobi P.O. Box 30709-00100, Kenya.ORCID 0000-0003-1053-085X
International Livestock Research Institute · KEJomo Kenyatta University of Agriculture and Technology · KEKenya Wildlife Service · KEThe Ohio State University · US

Funding

Defense Threat Reduction Agency HDTRA1-16-1-0050
6 · The paper itself

Abstract

Swine leukocyte antigen (SLA) plays a central role in controlling the immune response by discriminating self and foreign antigens and initiating an immune response. Studies on SLA polymorphism have demonstrated associations between SLA allelic variants, immune response, and disease resistance. The SLA polymorphism is due to host-pathogen co-evolution resulting in improved adaptation to diverse environments making SLA a crucial genomic region for comparative diversity studies. Although locally-adapted African pigs have small body sizes, they possess increased resilience under harsh environmental conditions and robust immune systems with reported tolerance to some diseases, including African swine fever. However, data on the SLA diversity in these pigs are not available. We characterized the SLA of unrelated locally-adapted domestic pigs from Homa Bay, Kenya, alongside exotic pigs and warthogs. We undertook SLA comparative diversity of the functionally expressed SLA class I (

Indexed as

diversitydomestic pigsDQB1locally-adapted pigsMHCPBRSLAwarthogs

Identifiers

PMID34564574
PMCPMC8473215
OpenAlexW3196620702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.