Evidence map›Paper›PMID 34564519›Full record

ReviewMembranes2021

Bioactive Agent-Loaded Electrospun Nanofiber Membranes for Accelerating Healing Process: A Review.

Seyyed-Mojtaba Mousavi, Zohre Mousavi Nejad, Seyyed Alireza Hashemi, Marjan Salari, Ahmad Gholami, Seeram Ramakrishna, Wei-Hung Chiang, Chin Wei Lai

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Membranes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. A Systematic Review of the Effect ofInternational journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Seyyed-Mojtaba MousaviDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan.
Zohre Mousavi NejadBiotechnology Research Center and Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Shiraz University of Medical Science, Shiraz 71345-1583, Iran.ORCID 0000-0002-5989-2491
Seyyed Alireza HashemiNanomaterials and Polymer Nanocomposites Laboratory, School of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada.
Marjan SalariDepartment of Civil Engineering, Sirjan University of Technology, Sirjan CM7X+MCX, Iran.ORCID 0000-0003-1742-0485
Ahmad GholamiBiotechnology Research Center and Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Shiraz University of Medical Science, Shiraz 71345-1583, Iran.ORCID 0000-0003-1851-159X
Seeram RamakrishnaCenter for Nanofibers and Nanotechnology, Department of Mechanical Engineering, National University of Singapore, Singapore 117576, Singapore.ORCID 0000-0001-8479-8686
Wei-Hung ChiangDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan.ORCID 0000-0002-6350-6696
Chin Wei LaiNanotechnology and Catalysis Research Centre (NANOCAT), Institute for Advanced Studies (IAS), University of Malaya (UM), 50603 Kuala Lumpur, Malaysia.ORCID 0000-0002-7549-5015
National Taiwan University of Science and Technology · TWShiraz University · IRNational University of Singapore · SGSirjan University of Technology · IRUniversity of British Columbia · CAUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the advances that have been achieved in developing wound dressings to date, wound healing still remains a challenge in the healthcare system. None of the wound dressings currently used clinically can mimic all the properties of normal and healthy skin. Electrospinning has gained remarkable attention in wound healing applications because of its excellent ability to form nanostructures similar to natural extracellular matrix (ECM). Electrospun dressing accelerates the wound healing process by transferring drugs or active agents to the wound site sooner. This review provides a concise overview of the recent developments in bioactive electrospun dressings, which are effective in treating acute and chronic wounds and can successfully heal the wound. We also discuss bioactive agents used to incorporate electrospun wound dressings to improve their therapeutic potential in wound healing. In addition, here we present commercial dressings loaded with bioactive agents with a comparison between their features and capabilities. Furthermore, we discuss challenges and promises and offer suggestions for future research on bioactive agent-loaded nanofiber membranes to guide future researchers in designing more effective dressing for wound healing and skin regeneration.

Indexed as

bioactive moleculeselectrospinningtissue engineeringwound dressingwound healing

Identifiers

PMID34564519
PMCPMC8469443
OpenAlexW3199798879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.