ArticleMetabolites2021
Correlation between Pre-Ovulatory Follicle Diameter and Follicular Fluid Metabolome Profiles in Lactating Beef Cows.
Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- A Follicle Size Window of Competence for In Vitro Embryo Production in High-Producing Dairy Cows: Evidence from OPU-IVP Performance and Follicular Fluid Profiling.Animals : an open access journal from MDPI · 2026Article
- Effects of Dried Distillers Grains in Supplements for Beef Cows During Late Gestation on Cow-Calf Performance and Metabolic Status.Animals : an open access journal from MDPI · 2025Article
- Transcriptome profiles of blastocysts originating from oocytes matured in follicular fluid from preovulatory follicles of greater or lesser maturity.BMC genomics · 2025Article
- Metabolomic Biomarkers in Bovine Embryo Culture Media and Their Relationship with the Developmental Potential of In Vitro-Produced Embryos.International journal of molecular sciences · 2025Article
- β-hydroxybutyrate induces endoplasmic reticulum stress in bovine cumulus cells during oocyte maturationAnimal reproduction · 2025Article
- Unravelling the Signature Follicular Fluid Metabolites in Dairy Cattle Follicles Growing Under Negative Energy Balance: An In Vitro Approach.International journal of molecular sciences · 2024Article
- The dose-dependent dual effects of alpha-ketoglutarate (AKG) on cumulus oocyte complexes during in vitro maturation.Cell communication and signaling : CCS · 2024Article
- Factors defining developmental competence of bovine oocytes collected for in vitro embryo production†.Biology of reproduction · 2024Review
- Impact of preovulatory follicle maturity on oocyte metabolism and embryo development.PNAS nexus · 2024Article
- Higher abundance of 2-dehydro-d-gluconate in the plasma of sub-fertile or infertile Bos taurus heifers.Journal of animal science · 2024Article
- Increased serine synthesis in cumulus cells of young infertile women with diminished ovarian reserve.Human reproduction (Oxford, England) · 2023Article
- Acid-Base, Gas, Ions, and Glucose Analysis in Follicular Fluid in Holstein-Friesian Dairy Cows Is Associated with the Follicle Size in Poland.Animals : an open access journal from MDPI · 2023Article
- Metabolite abundance in bovine preovulatory follicular fluid is influenced by follicle developmental progression post estrous onset in cattle.Frontiers in cell and developmental biology · 2023Article
- Metabolic signatures in human follicular fluid identify lysophosphatidylcholine as a predictor of follicular development.Communications biology · 2022Article
- Preovulatory serum estradiol concentration is positively associated with oocyte ATP and follicular fluid metabolite abundance in lactating beef cattle.Journal of animal science · 2022Article
- Preovulatory follicle contributions to oocyte competence in cattle: importance of the ever-evolving intrafollicular environment leading up to the luteinizing hormone surge.Journal of animal science · 2022Review
- Preovulatory follicular fluid and serum metabolome profiles in lactating beef cows with thin, moderate, and obese body condition.Journal of animal science · 2022Article
- Effects of nicotinamide on follicular development and the quality of oocytes.Reproductive biology and endocrinology : RB&E · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Induced ovulation of small pre-ovulatory follicles reduced pregnancy rates, embryo survival, day seven embryo quality, and successful embryo cleavage in beef cows undergoing fixed-time artificial insemination. RNA-sequencing of oocytes and associated cumulus cells collected from pre-ovulatory follicles 23 h after gonadotropin-releasing hormone (GnRH) administration to induce the pre-ovulatory gonadotropin surge suggested reduced capacity for glucose metabolism in cumulus cells of follicles ≤11.7 mm. We hypothesized that the follicular fluid metabolome influences metabolic capacity of the cumulus-oocyte complex and contributes to reduced embryo cleavage and quality grade observed following induced ovulation of small follicles. Therefore, we performed a study to determine the correlation between pre-ovulatory follicle diameter and follicular fluid metabolome profiles in lactating beef cows (Angus,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.