Evidence map›Paper›PMID 34564392›Full record

ArticleMetabolites2021

Radial Flow Perfusion Enables Real-Time Profiling of Cellular Metabolism at Low Oxygen Levels with Hyperpolarized

Anthony Mancuso, Mehrdad Pourfathi, Ryan M Kiefer, Michael C Noji, Sarmad Siddiqui, Enri Profka, Charles N Weber, Austin Pantel, Stephen J Kadlecek, Rahim Rizi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anthony MancusoAbramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mehrdad PourfathiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ryan M KieferDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Michael C NojiDepartment of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sarmad SiddiquiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Enri ProfkaDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Charles N WeberDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Austin PantelDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Stephen J KadlecekDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rahim RiziDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Terence P F GadeAbramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
National Insti-tutes of Health Early Independence Award DP5OD021391The National Center for Advancing Translational Sci-ences UL1TR000003The National Center for Research Resources UL1RR024134The National Institute for Biomedical Imaging and Bioengineering T32 EB00431112
6 · The paper itself

Abstract

In this study, we describe new methods for studying cancer cell metabolism with hyperpolarized

Indexed as

cell immobilizationDNPhyperpolarized 13CmicrocarriersNMR spectroscopyoxygen transportperfusionradial flow

Identifiers

PMID34564392
PMCPMC8465580

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.