Evidence map›Paper›PMID 34564375›Full record

ReviewToxics2021

Microplastics in the Environment: Intake through the Food Web, Human Exposure and Toxicological Effects.

Concetta Pironti, Maria Ricciardi, Oriana Motta, Ylenia Miele, Antonio Proto, Luigi Montano

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06107933 (Developmental Impacts of MicroPLastics Exposure in Early Life), which is not on this map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06107933 recruitingnot on this mapstarted 2023, after this paper: background citation

Developmental Impacts of MicroPLastics Exposure in Early Life

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2023 to 2027Enrolled40ConditionsInfant Development, Breast Feeding, Environmental ExposureArmsObservational only
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 318 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Microplastics in the Female Genital Tract and Fetoplacental Continuum: A Lesion-Based Framework for Pathophysiological Interpretation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. [Microplastic and skin-an update].Dermatologie (Heidelberg, Germany) · 2026
    Review
  17. Review
  18. Observational
  19. Review
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Concetta PirontiDepartment of Medicine Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
Maria RicciardiDepartment of Medicine Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0002-4668-2380
Oriana MottaDepartment of Medicine Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0003-1088-6741
Ylenia MieleDepartment of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano, Italy.ORCID 0000-0001-9330-2152
Antonio ProtoDepartment of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano, Italy.
Luigi MontanoAndrology Unit and Service of Lifestyle Medicine in UroAndrology, Local Health Authority (ASL) Salerno, Coordination Unit of the Network for Environmental and Reproductive Health (Eco-FoodFertility Project), "S. Francesco di Assisi Hospital", 84020 Oliveto Citra, Italy.
University of Salerno · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, studies on microplastics (MPs) have increased rapidly due to the growing awareness of the potential health risks related to their occurrence. The first part of this review is devoted to MP occurrence, distribution, and quantification. MPs can be transferred from the environment to humans mainly through inhalation, secondly from ingestion, and, to a lesser extent, through dermal contact. As regards food web contamination, we discuss the microplastic presence not only in the most investigated sources, such as seafood, drinking water, and salts, but also in other foods such as honey, sugar, milk, fruit, and meat (chickens, cows, and pigs). All literature data suggest not-negligible human exposure to MPs through the above-mentioned routes. Consequently, several research efforts have been devoted to assessing potential human health risks. Initially, toxicological studies were conducted with aquatic organisms and then with experimental mammal animal models and human cell cultures. In the latter case, toxicological effects were observed at high concentrations of MPs (polystyrene is the most common MP benchmark) for a short time. Further studies must be performed to assess the real consequences of MP contamination at low concentrations and prolonged exposure.

Indexed as

environmentfood webhuman exposuremicroplasticnanoplastictoxicological effects

Identifiers

PMID34564375
PMCPMC8473407
OpenAlexW3200098457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.